J Oral Facial Pain Headache. 2018;32(2):e13-e21. doi: 10.11607/ofph.1955.
To evaluate the effectiveness and safety of botulinum toxin administration into the inferior head of the lateral pterygoid muscle of patients with jaw opening dystonia by using a computer-aided design/computer-assisted manufacture (CAD/CAM)-derived needle guide.
A total of 17 patients with jaw opening dystonia were enrolled. After the patient's computed tomography (CT) scan was imported and fused with a scan of a plaster cast model of the maxilla, the optimal needle insertion site over the lateral pterygoid muscle was determined using the NobelClinician software. A total of 13 patients were injected both with and without the guide, and 4 patients underwent guided injection alone. The therapeutic effects of botulinum toxin injection and its associated complications were statistically compared between the guided and unguided procedures using paired t test.
Botulinum toxin therapy was performed 42 and 32 times with and without the guides, respectively. The needle was easily inserted without any complications in all procedures. There was a significant difference (P < .001) between the mean comprehensive improvements observed with (66.3%) and without (54.4%) the guides.
The findings suggest that the use of needle guides during the injection of botulinum toxin into the inferior head of the lateral pterygoid muscle is very useful for aiding the accurate and safe administration of botulinum toxin therapy for jaw opening dystonia.
通过使用计算机辅助设计/计算机辅助制造 (CAD/CAM) 衍生的针引导器，评估将肉毒毒素注射到翼外肌下头部在治疗开口下颌肌张力障碍患者中的有效性和安全性。
共纳入 17 例开口下颌肌张力障碍患者。在将患者的计算机断层扫描 (CT) 扫描导入并与上颌石膏模型的扫描融合后，使用 NobelClinician 软件确定穿过翼外肌的最佳针插入点。共有 13 名患者在有和没有引导器的情况下进行了注射，4 名患者仅进行了引导注射。使用配对 t 检验对引导和非引导程序的肉毒毒素注射治疗效果及其相关并发症进行统计学比较。
分别有 42 次和 32 次注射有和没有引导器。在所有手术中，针都很容易插入，没有任何并发症。有引导（66.3%）和无引导（54.4%）时的综合改善平均值之间存在显著差异（P <.001）。
这些发现表明，在将肉毒毒素注射到翼外肌下头部时使用针引导器对于辅助准确和安全地进行治疗开口下颌肌张力障碍的肉毒毒素治疗非常有用。
