Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland.
Centre for Affective, Sleep and Stress Disorders, University Psychiatric Clinic, University of Basel, Basel, Switzerland.
Neuropsychobiology. 2017;76(2):59-71. doi: 10.1159/000486903. Epub 2018 Apr 25.
Deficits in psychological functioning, cognitive functioning, and sleep are frequently experienced by individuals who have survived aneurysmal subarachnoid haemorrhage (aSAH). Exercise has been shown to improve these domains; to date, it has never been explored in patients following aSAH. The aim of this exploratory study is to compare the effects of an exercise programme in this population with another patient group, and a group of healthy controls.
The present study explored the effects of 12 weeks of moderate aerobic exercise training on 15 aSAH patients, 16 meningioma patients, and 17 healthy controls. Data on symptoms of depression, hypochondria, perceived stress, satisfaction with life, verbal learning and memory, and subjective and objective sleep, were gathered at baseline, following intervention, and at 6-month follow-up.
aSAH patients and meningioma patients had decreased symptoms of depression and insomnia at follow-up. While perceived stress decreased in the meningioma group, in aSAH patients it increased. Total learning performance increased in all three groups.
An exercise programme had a positive effect on symptoms of depression, insomnia, and verbal learning in patients following aSAH. No positive changes in other domains were observed. This may be due to the cautious approach taken with regard to exercise intensity.
经历过脑动脉瘤性蛛网膜下腔出血（aSAH）的个体通常会出现心理功能、认知功能和睡眠方面的障碍。运动已被证明可以改善这些方面；迄今为止，尚未在 aSAH 患者中进行过探索。本探索性研究的目的是比较该人群中运动计划的效果与另一组患者和一组健康对照组的效果。
本研究探讨了 12 周中等强度有氧运动训练对 15 名 aSAH 患者、16 名脑膜瘤患者和 17 名健康对照者的影响。在基线、干预后和 6 个月随访时收集了抑郁、疑病症、感知压力、生活满意度、言语学习和记忆以及主观和客观睡眠等症状的数据。
aSAH 患者和脑膜瘤患者在随访时抑郁和失眠症状减轻。而脑膜瘤组的感知压力下降，aSAH 患者的感知压力则增加。所有三组的总学习成绩均提高。
运动计划对 aSAH 患者的抑郁、失眠和言语学习症状有积极影响。其他方面没有观察到积极的变化。这可能是由于对运动强度采取了谨慎的方法。
