Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Neurosurgery, Karolinska University hospital, Stockholm, Sweden.
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Neurosurgery, Karolinska University hospital, Stockholm, Sweden.
World Neurosurg. 2015 Jun;83(6):1090-7. doi: 10.1016/j.wneu.2014.12.027. Epub 2014 Dec 19.
To explore anxiety levels during the first 2 years after rupture of aneurysmal subarachnoid hemorrhage.
A consecutive sample of patients with aneurysmal subarachnoid hemorrhage (aSAH) (n = 88, 84.6% of eligible) from a Swedish neurosurgical clinic were followed-up with a prospective cohort design at 3 time points; 6 months, 1 year, and 2 years after the onset. Data were collected by postal questionnaires and telephone interviews: State trait anxiety inventory, Hospital anxiety and depression scales, Barthel index, Telephone interview for cognitive status, and a set of study-specific questions.
Most of the respondents scored above the State trait anxiety inventory Swedish norm value on anxiety levels at all 3 follow-up time points. About 59% (n = 52) of respondents scored above the cutoff value for clinical significant level of anxiety in at least 1 time point during the first 2 years after rupture of aSAH. There were no significant differences in levels of anxiety versus the observational period and the 3 follow-up time points. The most significant explanatory variable to high levels of anxiety at all 3 follow-up time points was low perceived recovery.
Levels of anxiety remained high and stable throughout the first 2 years after rupture of aSAH. High levels of anxiety may reduce health-related quality of life substantially. Identification of individuals with high levels of anxiety and supportive care could therefore potentially improve long-term outcome.
探讨破裂性颅内蛛网膜下腔出血后 2 年内的焦虑水平。
采用前瞻性队列设计，对瑞典神经外科诊所的连续样本患者（共 88 例，符合条件的患者 84.6%）进行随访，在发病后 6 个月、1 年和 2 年进行 3 次随访。通过邮寄问卷和电话访谈收集数据：状态特质焦虑量表、医院焦虑和抑郁量表、巴氏指数、电话认知状态测试以及一套特定于研究的问题。
大多数受访者在所有 3 个随访时间点的焦虑水平上均高于瑞典状态特质焦虑量表的正常值。约 59%（n=52）的受访者在破裂性颅内蛛网膜下腔出血后 2 年内至少有 1 次的焦虑水平超过临床显著水平的临界值。焦虑水平与观察期和 3 个随访时间点之间无显著差异。在所有 3 个随访时间点上，导致高焦虑水平的最显著解释变量是感知康复水平低。
破裂性颅内蛛网膜下腔出血后 2 年内，焦虑水平仍然很高且稳定。高焦虑水平可能会显著降低健康相关生活质量。因此，识别出有高水平焦虑的个体并提供支持性护理可能会潜在地改善长期预后。
