Zanjani Vagharedin Akhavan, Tabari Kasra, Sheikh-Al-Eslamian Seyedeh Mahsa, Abrandabadi Ahmad Najafi
Department of Restorative Dentistry, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dental Research Center, Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Med Life. 2018 Jan-Mar;11(1):51-56.
The development of new pulp capping agents has paved the way towards the preservation of pulp vitality, which is an important goal in restorative dentistry. This study sought to assess the calcium ion release, pH and setting of mineral trioxide aggregate (MTA) Angelus, an experimental formulation of nano-hybrid MTA containing nano-SiO2, nano-Al2O3 and nano-TiO2 and MTA Angelus plus nano-oxides. In this experimental study, five specimens from each material were placed in polypropylene tubes and immersed in a flask containing deionized distilled water. The amount of calcium ions released into the solution from each material was measured at 15 minutes, one hour and 24 hours using atomic absorption spectroscopy. The pH of the solutions was measured using a pH meter at the respective time points. Setting time was also assessed using a Gilmore needle. Data were analyzed using the repeated measures ANOVA. The amount of released calcium ions was not significantly different among the groups (P=0.060). All materials were alkaline and the pH at 24 hours was significantly higher than the other two time points in all groups (P<0.001). The experimental group had the shortest and MTA Angelus had the longest setting time. All materials were alkaline and capable of releasing calcium. Addition of nanoparticles to MTA Angelus significantly decreased the setting time but had no effect on the release of calcium ions or pH. mineral trioxide aggregate (MTA), vital pulp therapy (VPT).
新型牙髓盖髓剂的研发为保存牙髓活力铺平了道路，而牙髓活力保存是修复牙科的一个重要目标。本研究旨在评估三氧化矿物凝聚体（MTA）安吉利斯、一种含有纳米二氧化硅、纳米氧化铝和纳米二氧化钛的纳米混合MTA实验配方以及MTA安吉利斯加纳米氧化物的钙离子释放、pH值和凝固情况。在这项实验研究中，将每种材料的五个样本放入聚丙烯管中，并浸入装有去离子蒸馏水的烧瓶中。使用原子吸收光谱法在15分钟、1小时和24小时测量每种材料释放到溶液中的钙离子量。在各个时间点使用pH计测量溶液的pH值。凝固时间也使用吉尔摩针进行评估。数据使用重复测量方差分析进行分析。各组之间释放的钙离子量没有显著差异（P = 0.060）。所有材料均呈碱性，并且所有组在24小时时的pH值显著高于其他两个时间点（P < 0.001）。实验组的凝固时间最短，MTA安吉利斯的凝固时间最长。所有材料均呈碱性且能够释放钙离子。向MTA安吉利斯中添加纳米颗粒显著缩短了凝固时间，但对钙离子释放或pH值没有影响。三氧化矿物凝聚体（MTA），牙髓活力保存疗法（VPT）。
