Amini Ghazvini Sara, Abdo Tabrizi Maryam, Kobarfard Farzad, Akbarzadeh Baghban Alireza, Asgary Saeed
Researcher, Dental Research Center, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran Endod J. 2009 Spring;4(2):74-8. Epub 2009 Apr 17.
This in vitro study measured and compared pH and phosphate and calcium ions release of a new endodontic material (CEM cement), mineral trioxide aggregate (MTA), and Portland cement (PC) using UV-visible technique, atomic absorption spectrophotometry methods, and pH meter, respectively.
Each material was placed in a plastic tube (n=10) and immersed in a glass flask containing deionized water. Half of the samples were tested for determining pH and released ions after 1h, 3h, 24h, 48h, 7d and 28d. Remaining samples (n=5), were evaluated after 28d. Data was analyzed using one way ANOVA and Tukey tests.
Results indicated that all materials were highly alkaline and released calcium and low concentration of phosphate ions in all the time intervals. CEM cement released considerably higher concentration of phosphate during the first hour (P<0.05).
This novel endodontic cement promoted alkaline pH in a similar manner to MTA and released calcium and phosphate. These conditions can stimulate the calcification process and explain the basic physico-chemical mechanisms of hard tissue regeneration of CEM cement.
本体外研究分别使用紫外可见技术、原子吸收分光光度法和pH计测量并比较了一种新型根管治疗材料（CEM水门汀）、三氧化矿物凝聚体（MTA）和波特兰水泥（PC）的pH值以及磷酸盐和钙离子的释放情况。
将每种材料置于塑料管中（n = 10），并浸入装有去离子水的玻璃瓶中。一半样品在1小时、3小时、24小时、48小时、7天和28天后进行pH值和离子释放测定。其余样品（n = 5）在28天后进行评估。数据采用单因素方差分析和Tukey检验进行分析。
结果表明，所有材料均呈高碱性，且在所有时间间隔内均释放钙离子和低浓度的磷酸盐离子。CEM水门汀在最初一小时内释放的磷酸盐浓度显著更高（P < 0.05）。
这种新型根管治疗水门汀与MTA以相似的方式促进碱性pH值的产生，并释放钙离子和磷酸盐。这些条件可刺激钙化过程，并解释CEM水门汀硬组织再生的基本物理化学机制。
