Wang-Hall Jennifer, Li B U K, Tarbell Sally E
Pediatric Mental Health Institute, Children's Hospital Colorado, Aurora, CO.
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
J Pediatr Gastroenterol Nutr. 2018 May;66(5):738-743. doi: 10.1097/MPG.0000000000001797.
The aim of the study was to evaluate the relationship of disease characteristics and child anxiety symptoms to family health-related quality of life (FHRQoL) in youth with cyclic vomiting syndrome (CVS).
Forty-two parents of youth ages 8 to 18 years diagnosed with CVS completed the Family Impact Module of the PedsQL, a measure of the impact of the child's illness on the family. We evaluated the relationship of disease characteristics and child and parent proxy reports of anxiety symptoms on the Screen for Childhood Anxiety and Related Emotional Disorders to FHRQoL.
Parent report of child anxiety symptoms and missed school days (mean = 11.93, standard deviation = 14.62) were the strongest predictors of FHRQoL (r = 0.33, df = 1.39, F = 8.51, P = 0.006). Other disease characteristics, including frequency, duration, chronicity of CVS episodes, and delay in initial CVS diagnosis were not significantly associated with the FHRQoL total score. Child anxiety symptoms by either parent and/or child report were associated with subscales of the FHRQoL, including family physical functioning, family communication, and family daily activities.
HRQoL for the families assessed in this study was associated with anxiety symptoms to a greater extent than disease characteristics, indexing the importance of a biopsychosocial approach to CVS management. Screening for anxiety symptoms and support for school absences due to illness are indicated to help lessen the impact of CVS on the family as a whole.
本研究旨在评估周期性呕吐综合征（CVS）青少年的疾病特征和儿童焦虑症状与家庭健康相关生活质量（FHRQoL）之间的关系。
42名8至18岁被诊断为CVS的青少年的父母完成了儿童生活质量量表（PedsQL）的家庭影响模块，该量表用于衡量儿童疾病对家庭的影响。我们评估了疾病特征以及儿童和父母关于儿童焦虑症状的代理报告（通过儿童焦虑及相关情绪障碍筛查量表）与FHRQoL之间的关系。
父母报告的儿童焦虑症状和缺课天数（均值 = 11.93，标准差 = 14.62）是FHRQoL最强的预测因素（r = 0.33，自由度 = 1.39，F = 8.51，P = 0.006）。其他疾病特征，包括CVS发作的频率、持续时间、慢性程度以及初次CVS诊断的延迟，与FHRQoL总分无显著关联。父母和/或儿童报告的儿童焦虑症状与FHRQoL的子量表相关，包括家庭身体功能、家庭沟通和家庭日常活动。
本研究中评估的家庭的健康相关生活质量与焦虑症状的关联程度大于疾病特征，这表明生物心理社会方法在CVS管理中的重要性。建议筛查焦虑症状并为因病缺课提供支持，以帮助减轻CVS对整个家庭的影响。
