Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Retina. 2019 Jul;39(7):1265-1277. doi: 10.1097/IAE.0000000000002168.
To analyze the morphologic features of lacquer cracks (LCs), compare their detectability by different imaging instruments, and determine their progressive pattern.
The medical records of 47 highly myopic eyes of 33 patients with LCs were reviewed. Fundus fluorescein angiography was used as the primary method of identifying LCs, and the detection rate was compared with that by fundus autofluorescence and optical coherence tomography.
A total of 176 LCs were detected in the 47 eyes. Lacquer cracks were detected more frequently in the temporal (44.3%) than the inferior (30.7%), superior (17.0%), and nasal (8.0%) quadrants of the retina. The detection rate of LCs was 98% in fundus photographs and 85% by fundus autofluorescence and optical coherence tomography. A progression of the LCs was observed in 22 of the 41 eyes with a follow-up period of ≥1 year. The progression patterns were an increase in the number (18 of 41, including 5 eyes in which new LCs had a branching pattern), elongation (4 of 41), and progression to patchy atrophy (6 of 41).
Lacquer cracks can be detected noninvasively by fundus autofluorescence and optical coherence tomography; however, improvements are necessary to detect all of the lesions. Lacquer cracks frequently progress with time, and an increase in the number of LCs was the most frequent progression pattern.
分析漆裂纹（LCs）的形态特征，比较不同成像仪器对其的检测能力，并确定其进展模式。
回顾了 33 例 LCs 患者的 47 只高度近视眼中的病历。眼底荧光血管造影被用作识别 LCs 的主要方法，并比较了其与眼底自发荧光和光相干断层扫描的检测率。
在 47 只眼中共检测到 176 个 LCs。漆裂纹在视网膜的颞侧（44.3%）比下侧（30.7%）、上侧（17.0%）和鼻侧（8.0%）更频繁地被检测到。LCs 在眼底照片中的检出率为 98%，在眼底自发荧光和光相干断层扫描中的检出率为 85%。在 41 只具有≥1 年随访期的眼中，观察到 22 只 LCs 的进展。进展模式包括数量增加（41 只中的 18 只，包括 5 只出现分支模式的新 LCs）、延长（41 只中的 4 只）和进展为斑片状萎缩（41 只中的 6 只）。
LCs 可以通过眼底自发荧光和光相干断层扫描进行非侵入性检测；然而，需要改进以检测所有病变。LCs 随着时间的推移经常进展，LCs 数量的增加是最常见的进展模式。
