Department of Family and Community Medicine, Saint Louis University School of Medicine.
Department of Psychiatry, Washington University in St. Louis.
Health Psychol. 2018 May;37(5):407-416. doi: 10.1037/hea0000593.
Research has shown that posttraumatic stress disorder (PTSD) increases the risk of development of cardiometabolic disease (CMD) including cardiovascular disease and diabetes. Whether PTSD is also associated with behavioral risk factors (e.g., diet, exercise, smoking and obesity) for CMD, is less clear.
PubMed, Web of Science, and Scopus databases were searched to obtain papers published between 1980-2016. Studies were reviewed for quality using the Quality of Cohort screen. Significance values, odds ratios (OR), 95% confidence intervals (CI), and tests of homogeneity of variance were calculated.
A total of 1,349 studies were identified from our search and 29 studies met all eligibility criteria. Individuals with PTSD were 5% less likely to have healthy diets (pooled adjusted OR = 0.95; 95% CI: 0.92, 0.98), 9% less likely to engage in physical activity (pooled adjusted OR = 0.91; 95% CI: 0.88, 0.93), 31% more likely to be obese (pooled adjusted OR = 1.31; 95% CI:1.25, 1.38), and about 22% more likely to be current smokers (pooled adjusted OR = 1.22; 95% CI: 1.19, 1.26), than individuals without PTSD.
Evidence shows PTSD is associated with reduced healthy eating and physical activity, and increased obesity and smoking. The well-established association between PTSD and metabolic and cardiovascular disease may be partly due to poor diet, sedentary lifestyle, high prevalence of obesity, and co-occurring smoking in this population. The well-established association of PTSD with CMD is likely due in part to poor health behaviors in this patient population. (PsycINFO Database Record
研究表明创伤后应激障碍(PTSD)会增加患心血病代谢疾病(CMD)的风险,包括心血管疾病和糖尿病。然而,PTSD 是否也与 CMD 的行为危险因素(如饮食、运动、吸烟和肥胖)有关,目前尚不清楚。
检索了 1980 年至 2016 年间发表的文献,检索数据库包括 PubMed、Web of Science 和 Scopus。使用队列研究质量评价工具(Quality of Cohort screen)对研究进行质量评价。计算了显著性值、比值比(OR)、95%置信区间(CI)和方差同质性检验。
从我们的检索中总共确定了 1349 项研究,其中 29 项研究符合所有入选标准。患有 PTSD 的个体更不可能有健康的饮食(合并调整后的 OR = 0.95;95%CI:0.92,0.98),不太可能进行体育锻炼(合并调整后的 OR = 0.91;95%CI:0.88,0.93),更有可能肥胖(合并调整后的 OR = 1.31;95%CI:1.25,1.38),更有可能是当前吸烟者(合并调整后的 OR = 1.22;95%CI:1.19,1.26),而不是没有 PTSD 的个体。
有证据表明,PTSD 与健康饮食和体育活动减少以及肥胖和吸烟增加有关。PTSD 与代谢和心血管疾病之间的既定关联部分可能是由于该人群中不良的饮食、久坐的生活方式、肥胖的高发率和同时存在的吸烟。PTSD 与 CMD 的既定关联可能部分归因于该患者群体中的不良健康行为。