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二叶式主动脉瓣主动脉根部和升主动脉手术后主动脉弓的转归。

Fate of the Aortic Arch Following Surgery on the Aortic Root and Ascending Aorta in Bicuspid Aortic Valve.

机构信息

Department of Cardiothoracic Surgery, St. George's Hospital, London, United Kingdom.

Department of Clinical Perfusion, St. George's Hospital, London, United Kingdom.

出版信息

Ann Thorac Surg. 2018 Sep;106(3):771-776. doi: 10.1016/j.athoracsur.2018.03.052. Epub 2018 Apr 23.

Abstract

BACKGROUND

Recent guidelines support more aggressive surgery for aneurysms of the ascending aorta and root in patients with bicuspid aortic valve. However, the fate of the arch after surgery of the root and ascending aorta is unknown. We set out to assess outcomes following root and ascending aortic surgery and subsequent growth of the arch.

METHODS

Between 2005 and 2016, 536 consecutive patients underwent surgery for aneurysm of the root and ascending aorta; 168 had bicuspid aortic valve. Patients with dissection were excluded. Arch diameter was measured before and after surgery, at 6 months and then annually.

RESULTS

Of 168 patients, 127 (75.6%) had aortic root replacement and 41 (24.4%) had ascending replacement. Mean age was 57 ± 12.8 years, 82.7% were men, and 5 operations were performed during pregnancy. There was 1 (0.6%) hospital death. One (0.6%) patient had a stroke and 1 (0.6%) had resternotomy for bleeding. Median intensive care unit and hospital stays were 1 and 6 days, respectively. Follow-up was complete for 94% at a median of 5.9 years (range, 1 to 139 months). Aortic arch diameter was 2.9 cm preoperatively and 3.0 cm at follow-up. There was 97% freedom from reoperation and none of the patients required surgery on the arch.

CONCLUSIONS

Prophylactic arch replacement during aortic root and ascending aortic surgery in patients with bicuspid aortic valve is not supported. Our data do not support long-term surveillance of the rest of the aorta in this population.

摘要

背景

最近的指南支持在患有二叶式主动脉瓣的患者中对升主动脉和根部的动脉瘤进行更积极的手术。然而,根部和升主动脉手术后弓部的命运尚不清楚。我们着手评估根部和升主动脉手术后以及弓部随后生长的结果。

方法

在 2005 年至 2016 年间,536 例连续的升主动脉根部动脉瘤患者接受了手术治疗;其中 168 例患者患有二叶式主动脉瓣。排除夹层患者。在手术前后、术后 6 个月和每年测量弓部直径。

结果

在 168 例患者中,127 例(75.6%)行主动脉根部置换术,41 例(24.4%)行升主动脉置换术。平均年龄为 57 ± 12.8 岁,82.7%为男性,5 例手术在妊娠期间进行。有 1 例(0.6%)院内死亡。1 例(0.6%)患者发生中风,1 例(0.6%)患者因出血再次开胸。重症监护病房和住院中位数分别为 1 天和 6 天。94%的患者获得了中位数为 5.9 年(范围 1 至 139 个月)的完整随访。术前主动脉弓部直径为 2.9cm,随访时为 3.0cm。无再次手术,无患者需要进行弓部手术。

结论

在二叶式主动脉瓣患者中,预防性主动脉根部和升主动脉手术中不支持置换弓部。我们的数据不支持在该人群中对主动脉其余部分进行长期监测。

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