家兔（穴兔）连锁群VI与啮齿类动物的染色体同源性。
Chromosomal homology of rabbit (Oryctolagus cuniculus) linkage group VI with rodent species.
作者信息
Fox R R, van Zutphen L F
出版信息
Genetics. 1979 Sep;93(1):183-8. doi: 10.1093/genetics/93.1.183.
Abstract
Homologous portions of linkage group (LG) VI in the rabbit Oryctolagus cuniculus, chromosome 8 in Mus musculus, and LG V of Rattus norvegicus have been observed. These linkage groups in Oryctolagus and Mus contain the extension locus (e), where recessive alleles are known in many species. Preliminary linkage data have added new loci to linkage group VI of the rabbit, revised the order and map distances on the linkage map, and by comparison with rodent species have strengthened the homology of LG VI in the rabbit with chromosome 8 of the mouse and with LG V of the rat. LG VI now contains five loci with the following order and intervening map distances: Es-1, Es-2 complex--6.3 +/- 2.1 cM--Est-1, Est-2 complex--18.5 +/- 3.7 cM--e.
摘要
已观察到家兔穴兔连锁群（LG）VI的同源部分、小家鼠的8号染色体以及褐家鼠的LG V。穴兔和小家鼠的这些连锁群包含扩展基因座（e），在许多物种中已知有隐性等位基因。初步的连锁数据为家兔的连锁群VI增添了新基因座，修订了连锁图谱上的顺序和图距，并且通过与啮齿动物物种比较，加强了家兔LG VI与小鼠8号染色体以及大鼠LG V的同源性。LG VI现在包含五个基因座，顺序如下，中间的图距为：Es-1、Es-2复合体——6.3±2.1厘摩——Est-1、Est-2复合体——18.5±3.7厘摩——e。
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