Department of Advanced Science and Technology , Japan Advanced Institute of Science and Technology , Asahidai 1-1 , Nomi , Ishikawa, 923-1292 , Japan.
Org Lett. 2018 May 18;20(10):2802-2805. doi: 10.1021/acs.orglett.8b00593. Epub 2018 Apr 27.
This report presents a novel photo-cross-linker that can cross-link to pyrimidines in nucleic acids under visible light irradiation (λ > 400 nm). This method offers ultrafast photo-cross-linking without any cytotoxicity due to UV irradiation.
本报告介绍了一种新型光交联剂，它可以在可见光（λ>400nm）照射下与核酸中的嘧啶发生交联。该方法无需紫外光照射即可实现超快光交联，且无细胞毒性。
