Tulane University School of Medicine, New Orleans, LA.
Tulane University School of Medicine, New Orleans, LA; Stanford University, Stanford, CA.
J Am Acad Child Adolesc Psychiatry. 2018 May;57(5):329-335.e2. doi: 10.1016/j.jaac.2018.02.009. Epub 2018 Mar 15.
Disinhibited social engagement disorder (DSED) is poorly understood beyond early childhood. The course of DSED signs in a sample of children who experienced severe, early deprivation from early childhood to early adolescence was examined using variable-centered (linear mixed modeling) and person-centered (growth mixture modeling) approaches.
The study included 124 children with a history of institutional care from a randomized controlled trial of foster care as an alternative to institutional care and 69 community comparison children matched by age and sex. DSED signs were assessed at baseline (mean age 22 months), 30, 42, and 54 months of age, and 8 and 12 years of age using a validated caregiver report of disturbed attachment behavior.
Variable-centered analyses based on intent-to-treat groups indicated that signs of DSED decreased sharply for children randomized to foster care and decreased slightly but remained high for children randomized to care as usual. Person-centered analyses showed 4 profiles (i.e., elevated, persistent modest, early decreasing, and minimal). Elevated and persistent modest courses were associated with greater placement disruptions (F = 4.29, p = .007, partial eta-squared [η] = 0.12), older age at placement into foster care (F = 3.41, p < .05, partial η = 0.16), and more time in institutional care (F = 11.91, p < .001, partial η = 0.24) compared with decreasing and minimal courses.
Early and sustained placement into families after deprivation is associated with minimal or decreasing signs of DSED across development. Shortening the amount of time children spend in institutions and preserving placements could help decrease signs of DSED into early adolescence in previously institutionalized children.
除了幼儿期之外,对去抑制型社交参与障碍(DSED)的了解甚少。使用变量中心(线性混合建模)和个体中心(增长混合建模)方法,检查了在经历严重早期剥夺的儿童样本中 DSED 体征的过程,这些儿童的早期剥夺来自幼儿期到青春期早期。
该研究包括来自寄养作为机构护理替代方案的随机对照试验的 124 名有机构护理史的儿童和 69 名按年龄和性别匹配的社区对照儿童。使用经过验证的照顾者报告的受干扰的依恋行为,在基线(平均年龄 22 个月)、30、42 和 54 个月以及 8 和 12 岁时评估 DSED 体征。
基于意向治疗组的变量中心分析表明,寄养组的 DSED 体征急剧下降,而常规护理组的 DSED 体征略有下降但仍保持较高水平。个体中心分析显示出 4 种特征(即升高、持续适度、早期下降和最小)。升高和持续适度的病程与更多的安置中断有关(F=4.29,p=0.007,部分η平方[η]=0.12),安置进入寄养的年龄较大(F=3.41,p<0.05,部分η=0.16),以及在机构中度过的时间更长(F=11.91,p<0.001,部分η=0.24)与下降和最小的病程相比。
在剥夺后尽早和持续地安置在家庭中与整个发展过程中 DSED 体征的最小或下降有关。缩短儿童在机构中度过的时间并保留安置位置可以帮助减少以前机构化儿童进入青春期早期的 DSED 体征。