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应用5%维生素C浓缩液后对选定皮肤参数的评估。

Evaluation of selected skin parameters following the application of 5% vitamin C concentrate.

作者信息

Jaros Anna, Zasada Malwina, Budzisz Elżbieta, Dębowska Renata, Gębczyńska-Rzepka Monika, Rotsztejn Helena

机构信息

Department of Cosmetic Raw Materials Chemistry, Faculty of Pharmacy, Medical University of Lodz, Lodz, Poland.

Centre for Science and Research Dr Irena Eris, Warsaw, Poland.

出版信息

J Cosmet Dermatol. 2019 Feb;18(1):236-241. doi: 10.1111/jocd.12562. Epub 2018 Apr 30.

Abstract

BACKGROUND

Ascorbic acid is a substance with confirmed anti-free-radical properties. It triggers the collagen synthesis, has a depigmenting effect and seals blood vessels. All these properties have a significant effect of the skin's appearance. The characteristic traits of capillary skin include telangiectasias as well as erythema, which might consolidate in the future, along with the feeling of burning and increased skin sensitivity.

OBJECTIVES

Study and evaluation of selected parameters of capillary skin after the application of 5% vitamin C concentrate throughout the period of 6 weeks with the use of instrumental tests and questionnaires.

METHODS

The research was conducted on a group of 30 women ranging from 30 to 60 years of age with capillary skin indicating visible signs of erythematous plaques. The concentrate was applied once a day. Analyses of skin conditions were conducted four times: before the launch of the research D(0), after two 2D(14), after four 4D(28), and after 6 D(42) weeks of application. The research was conducted with the use of Mexameter MPA equipment, which was used to measure changes in the intensity of erythematous plaques. The depth of wrinkles was measured by PRIMOS system (two times D0 and 6D(42). The research also used VISIA system which allowed to perform visual and numeral skin analyses. Each research was finalized with a questionnaire which provided a subjective evaluation of the examined product among participants.

RESULTS

Significant reduction in erythema has been widely recorded. After 2 weeks, erythema dropped by 9%. After 4 weeks, it decreased by 16% and by 21% after 6 weeks. The concentrate's efficiency in diminishing erythematous plaques was confirmed by photographs generated by VISIA photograph system. Thanks to PRIMOS, decrease in both depth and volume of nasolabial folds was recorded in 87% of participants after 6 weeks of research.

CONCLUSION

5% vitamin C concentrate is effective in treating capillary and photograph-aging skin. It decreases erythema and telangiectasias as well as triggers the shallowing of skin wrinkles.

摘要

背景

抗坏血酸是一种具有确切抗自由基特性的物质。它能促进胶原蛋白合成,具有美白作用并能封闭血管。所有这些特性对皮肤外观都有显著影响。毛细血管扩张性皮肤的特征包括毛细血管扩张以及红斑,未来可能会加重,同时伴有灼烧感和皮肤敏感性增加。

目的

通过仪器测试和问卷调查,研究并评估在6周时间内涂抹5%维生素C浓缩液后毛细血管扩张性皮肤的选定参数。

方法

对30名年龄在30至60岁之间、患有毛细血管扩张性皮肤且有明显红斑迹象的女性进行了研究。浓缩液每天涂抹一次。在研究开始前(D0)、涂抹两周后(D14)、四周后(D28)以及六周后(D42)对皮肤状况进行了四次分析。使用Mexameter MPA设备进行研究,该设备用于测量红斑强度的变化。皱纹深度通过PRIMOS系统测量(在D0和D42时各测量两次)。研究还使用了VISIA系统,该系统可进行皮肤的视觉和数字分析。每次研究最后都通过一份问卷让参与者对所测试产品进行主观评价。

结果

广泛记录到红斑有显著减少。两周后,红斑减少了9%。四周后,减少了16%,六周后减少了21%。VISIA照片系统生成的照片证实了浓缩液在减少红斑方面的效果。借助PRIMOS系统,研究六周后,87%的参与者鼻唇沟的深度和体积都有所减少。

结论

5%维生素C浓缩液对治疗毛细血管扩张性和光老化皮肤有效。它能减少红斑和毛细血管扩张,还能使皮肤皱纹变浅。

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