具有响应性外壳的核壳冠层胶束

Core-Shell-Corona Micelles with a Responsive Shell.

作者信息

Gohy Jean-François, Willet Nicolas, Varshney Sunil, Zhang Jian-Xin, Jérôme Robert

机构信息

Center for Education and Research on Macromolecules University of Liège Sart-Tilman, B6, 4000 Liège (Belgium) Fax: (+32) 4-3663497.

Polymer Source 771 Lajoie Street, Dorval, PQ H9P 1G7 (Canada).

出版信息

Angew Chem Int Ed Engl. 2001 Sep 3;40(17):3214-3216. doi: 10.1002/1521-3773(20010903)40:17<3214::AID-ANIE3214>3.0.CO;2-F.

DOI:10.1002/1521-3773(20010903)40:17<3214::AID-ANIE3214>3.0.CO;2-F

PMID:29712069

Abstract

A reactor for the synthesis of gold nanoparticles is one of the uses of a poly(styrene)-block-poly(2-vinylpyridine)-block-poly(ethylene oxide) triblock copolymer (PS-b-P2VP-b-PEO) which forms core-shell-corona micelles in water. Very low polydispersity spherical micelles are observed that consist of a PS core surrounded by a pH-sensitive P2VP shell and a corona of PEO chains end-capped by a hydroxyl group. The corona can act as a site for attaching responsive or sensing molecules.

摘要

用于合成金纳米颗粒的反应器是聚（苯乙烯）-嵌段-聚（2-乙烯基吡啶）-嵌段-聚（环氧乙烷）三嵌段共聚物（PS-b-P2VP-b-PEO）的用途之一，该共聚物在水中形成核壳-冠层胶束。观察到具有非常低多分散性的球形胶束，其由被pH敏感的P2VP壳包围的PS核以及由羟基封端的PEO链冠层组成。冠层可作为连接响应或传感分子的位点。