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印度中部药物治疗腕管综合征缓解的决定因素:一项研究

Determinants of Remission in Medically Treated Carpal Tunnel Syndrome: Study from Central India.

作者信息

Sodani Ajoy, Dani Raunak, Dube Mukesh, Choukesey Dinesh, Athale Sunil

机构信息

Department of Neurology, Sri Aurobindo Medical College and P. G. Institute, Indore, Madhya Pradesh, India.

出版信息

Ann Indian Acad Neurol. 2018 Jan-Mar;21(1):29-34. doi: 10.4103/aian.AIAN_347_17.

Abstract

BACKGROUND

The factors associated with the spontaneous remission (SR) of symptoms in carpal tunnel syndrome (CTS) are not well known.

OBJECTIVES

To look for determinants of SR in medically treated, electrophysiologically proven patients of CTS.

METHODS

We revisited the medical records and nerve conduction study data of 130 hands with CTS and divided them into two groups as per the absence or persistence of the symptoms when contacted after a median time lapse of 3 years following the diagnosis.

RESULTS

SR occurred in 46.1% of the hands. Higher odds of SR were linked with female gender, symptoms restriction to lateral fingers, symptom duration <10 months, mildly delayed median motor and sensory distal latencies, and median sensory amplitude >20 μV. We developed a seven-point scale, on which a score of ≥4 had a strong association (odds ratio 4.31) with SR.

DISCUSSION AND CONCLUSION

No single risk factor, standalone, can predict SR in patients with CTS, which could lead to an invasive treatment (Surgery or local injection) to them. We propose that patients scoring ≥4 on our 7 point scale should be treated medically for the initial 10 months after the symptom onset.

摘要

背景

腕管综合征(CTS)症状自发缓解(SR)相关因素尚不明确。

目的

在经医学治疗且经电生理证实的CTS患者中寻找SR的决定因素。

方法

我们回顾了130例CTS患者手部的病历和神经传导研究数据,并根据诊断后中位时间间隔3年随访时症状是否消失或持续,将其分为两组。

结果

46.1%的手部出现SR。SR的较高几率与女性、症状局限于外侧手指、症状持续时间<10个月、正中运动和感觉远端潜伏期轻度延迟以及正中感觉波幅>20μV有关。我们制定了一个七点量表,得分≥4与SR有很强的关联(优势比4.31)。

讨论与结论

没有单一危险因素能独立预测CTS患者的SR,这可能导致对他们进行侵入性治疗(手术或局部注射)。我们建议,在症状出现后的最初10个月内,对在我们七点量表上得分≥4的患者应进行药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f057/5909142/1a8e0f160e06/AIAN-21-29-g001.jpg

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