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首次从绵羊皮肤疣病变中检测到牛乳头瘤病毒 2 型。

First detection of bovine papillomavirus type 2 in cutaneous wart lesions from ovines.

机构信息

Laboratório de Genética, Instituto Butantan, Secretaria de Estado da Saúde, São Paulo, Brazil.

Programa de Pós-Graduação Interunidades em Biotecnologia, Universidade de São Paulo, São Paulo, Brazil.

出版信息

Transbound Emerg Dis. 2018 Aug;65(4):939-943. doi: 10.1111/tbed.12892. Epub 2018 May 3.

Abstract

This study diagnosed cutaneous wart lesions excised from three rams from a sheep farm in São Paulo State, Brazil. Histopathologically, these cases were diagnosed as papilloma. The amplification by PCR, sequencing and bioinformatics analysis showed that all the lesions presented DNA sequences of bovine papillomavirus type 2. This is the first report confirming the detection of BPV2 in papilloma warts from ovines.

摘要

本研究诊断了来自巴西圣保罗州一个绵羊养殖场的三只公羊的皮肤疣病变。组织病理学上,这些病例被诊断为乳头瘤。PCR 扩增、测序和生物信息学分析显示,所有病变均呈现牛乳头瘤病毒 2 型的 DNA 序列。这是首次证实 BPV2 在羊的乳头瘤样疣中的检测。

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