Korranne Vaishali, Merchant Yash, Joshi Samir, Halli Rajshekhar
Department of Oral Medicine and Radiology, Bharati Vidyapeeth University Dental College and Hospital, Pune, Maharashtra, India.
Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth University Dental College and Hospital, Pune, Maharashtra, India.
J Oral Maxillofac Pathol. 2018 Jan-Apr;22(1):150. doi: 10.4103/jomfp.JOMFP_144_16.
The dentinogenic ghost cell tumor (DGCT) is a relatively uncommon locally invasive neoplasm that mimics several inflammatory/reactive lesions of the gingiva or odontogenic cysts. The confirmatory diagnosis of this rare lesion can only be made with histopathological examination. Routine staining reveals features of a "mixed" tumor as ghost cells with calcification, dysplastic dentin and islands of epithelium in rosette pattern in mature connective tissue are visible. The case report describes an asymptomatic growth in the maxillary gingiva of a young patient that was incidentally diagnosed as a DGCT after biopsy. Malignant transformation of this lesion to its more aggressive counterpart, odontogenic ghost cell carcinoma has been described, and hence, regular follow-up of diagnosed cases is imperative. The purpose of the paper is to report a case that adds to the literature and this will consequently help to diagnose and understand the biological behavior of these lesions better.
牙源性影细胞肿瘤(DGCT)是一种相对罕见的局部侵袭性肿瘤,可模仿牙龈的几种炎症/反应性病变或牙源性囊肿。这种罕见病变的确诊只能通过组织病理学检查。常规染色显示为“混合性”肿瘤的特征,可见成熟结缔组织中有影细胞伴钙化、发育异常的牙本质以及呈玫瑰花结样排列的上皮岛。该病例报告描述了一名年轻患者上颌牙龈出现的无症状肿物,活检后偶然诊断为DGCT。已有该病变恶变为更具侵袭性的牙源性影细胞癌的报道,因此,对确诊病例进行定期随访至关重要。本文的目的是报告一例补充文献的病例,这将有助于更好地诊断和理解这些病变的生物学行为。