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200例复发性阿弗他口炎患者的临床研究

[Clinical study of 200 patients with recurrent aphthous stomatitis].

作者信息

Rodríguez-Archilla Alberto, Raissouni Tarik

机构信息

Universidad de Granada, Facultad de Odontología, Unidad de Medicina Bucal, Granada, España.

Centro Odontológico Mfedal Afailal Bab Okla, Tetuán, Marruecos.

出版信息

Gac Med Mex. 2018;154(2):165-171. doi: 10.24875/GMM.18002503.

DOI:10.24875/GMM.18002503
PMID:29733067
Abstract

INTRODUCTION

Recurrent aphthous stomatitis (RAS) affects approximately 20% of the general population. Its etiology is still unknown.

OBJECTIVE

To analyze this entity's clinical features.

METHOD

Data such as age, gender, family history of RAS, age at first episode onset, prodromal symptoms, number, size, morphology and localization of lesions, RAS clinical form, annual rate of recurrence, predisposing factors, symptoms and time for symptoms and lesions disappearance were assessed in 200 patients with RAS.

RESULTS

Patients had RAS minor forms. Main clinical characteristics were family history of RAS (89%), first episode at ≥ 10 years of age (69%), prodromal symptoms (66%), one lesion per episode (63%), < 0.5 cm lesions (64%), rounded morphology (55%), localization at the tongue (27%), 3 recurrent episodes per year (36%), stress as predisposing factor (34%), symptom disappearance in 2 days (54%) and healing of lesions in 8 days (40%).

CONCLUSION

Even when RAS is a common disorder of the oral mucosa, there is no curative treatment available. Therapeutic measures seek to reduce the pain and size of lesions, accelerate the time of recovery and decrease the rate of relapses.

摘要

引言

复发性阿弗他口炎(RAS)影响着约20%的普通人群。其病因仍不明。

目的

分析该疾病实体的临床特征。

方法

对200例RAS患者评估了年龄、性别、RAS家族史、首次发病年龄、前驱症状、病损数量、大小、形态和部位、RAS临床类型、年复发率、诱发因素、症状以及症状和病损消失时间等数据。

结果

患者患有轻型RAS。主要临床特征为RAS家族史(89%)、首次发病年龄≥10岁(69%)、前驱症状(66%)、每次发作一个病损(63%)、病损<0.5 cm(64%)、圆形形态(55%)、部位在舌部(27%)、每年复发3次(36%)、应激作为诱发因素(34%)、症状2天内消失(54%)以及病损8天愈合(40%)。

结论

即使RAS是口腔黏膜的常见疾病,但尚无治愈性治疗方法。治疗措施旨在减轻疼痛和缩小病损大小,加快恢复时间并降低复发率。

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