Department of Gastrointestinal Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, PR China.
Department of General Surgery, The Fifth People Hospital of Nanhai District, Foshan 528231, PR China.
Future Oncol. 2018 Jun;14(13):1307-1316. doi: 10.2217/fon-2017-0439. Epub 2018 May 9.
Accumulated evidence has shown that colonoscopy may not be a perfect tool in screening and reducing the incidence of the colorectal cancer (CRC), because interval CRC (I-CRC), a specific subgroup of CRCs, has been challenging the traditional detection technology in recent years. I-CRC is accounting for an increasing proportion in CRCs. However, the effective procedures to prevent and supervise I-CRC need to be explored. In this review, we summarized the incidence, causes, risk factors, characteristics and management of I-CRC. It would promote the awareness of the special value in the education and training for the gastroenterologists, which plays an important role in conquering CRC.
大量证据表明，结肠镜检查在筛查和降低结直肠癌（CRC）发病率方面可能不是一种完美的工具，因为近年来，结直肠癌的一个特定亚组——间期结直肠癌（I-CRC）一直对传统检测技术构成挑战。I-CRC 在 CRC 中的比例不断增加。然而，需要探索预防和监测 I-CRC 的有效程序。在这篇综述中，我们总结了 I-CRC 的发生率、原因、危险因素、特征和管理。这将提高胃肠病学家在教育和培训方面对其特殊价值的认识，这对于攻克 CRC 具有重要作用。
