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结直肠癌预防的新进展:筛查与监测。

Advances in CRC Prevention: Screening and Surveillance.

机构信息

Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States.

出版信息

Gastroenterology. 2018 May;154(7):1970-1984. doi: 10.1053/j.gastro.2018.01.069. Epub 2018 Feb 15.

Abstract

Colorectal cancer (CRC) is among the most commonly diagnosed cancers and causes of death from cancer across the world. CRC can, however, be detected in asymptomatic patients at a curable stage, and several studies have shown lower mortality among patients who undergo screening compared with those who do not. Using colonoscopy in CRC screening also results in the detection of precancerous polyps that can be directly removed during the procedure, thereby reducing the incidence of cancer. In the past decade, convincing evidence has appeared that the effectiveness of colonoscopy as CRC prevention tool is associated with the quality of the procedure. This review aims to provide an up-to-date overview of recent efforts to improve colonoscopy effectiveness by enhancing detection and improving the completeness and safety of resection of colorectal lesions.

摘要

结直肠癌(CRC)是世界范围内最常见的癌症之一,也是癌症死亡的主要原因。然而,CRC 可以在无症状患者中早期发现并治愈,多项研究表明,筛查患者的死亡率低于未筛查患者。在 CRC 筛查中使用结肠镜检查还可以检测到癌前息肉,并可在检查过程中直接切除,从而降低癌症的发病率。在过去十年中,令人信服的证据表明,结肠镜检查作为 CRC 预防工具的有效性与该程序的质量有关。本综述旨在提供最新的概述,介绍通过提高检测水平以及提高结直肠病变切除的完整性和安全性来提高结肠镜检查效果的最新努力。

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