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皮肤干细胞的静息、激活与癌变。

Skin Stem Cells in Silence, Action, and Cancer.

机构信息

Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA.

出版信息

Stem Cell Reports. 2018 May 8;10(5):1432-1438. doi: 10.1016/j.stemcr.2018.04.008.

Abstract

In studying how stem cells make and maintain tissues, nearly every chapter of a cell biology textbook takes on special interest. The field even allows us to venture where no chapters have yet been written. In studying this basic problem, we are continually bombarded by nature's surprises and challenges. Stem cell biology has captured my interest for nearly my entire scientific career. Below, I focus on my laboratory's contributions to this fascinating field, to which so many friends and colleagues have made seminal discoveries equally deserving of this award.

摘要

在研究干细胞如何生成和维持组织的过程中,细胞生物学教科书中的几乎每一章都具有特殊的意义。该领域甚至让我们有机会涉足尚未有章节涉及的领域。在研究这个基本问题的过程中,我们不断受到自然界的惊喜和挑战的冲击。干细胞生物学几乎贯穿了我整个科研生涯,是我最感兴趣的领域。下面,我将重点介绍我们实验室在这个迷人领域的贡献,许多朋友和同事也在这个领域做出了同样重要的开创性发现,他们都值得获得这个奖项。

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