金属孔隙率会影响全髋关节置换术后血液和尿液中的金属离子释放吗？一项短期研究。
Does metal porosity affect metal ion release in blood and urine following total hip arthroplasty? A short term study.
作者信息
Bistolfi Alessandro, Cimino Andrea, Lee Gwo-Chin, Ferracini Riccardo, Maina Giovanni, Berchialla Paola, Massazza Giuseppe, Massè Alessandro
机构信息
1 AO Città della Salute e della Scienza, Department of Orthopeadics, Traumatology and Rehabilitative Medicine, CTO Hospital, Turin, Italy.
2 University of the Studies of Turin, Turin, Italy.
出版信息
Hip Int. 2018 Sep;28(5):522-530. doi: 10.1177/1120700018762167. Epub 2018 May 9.
INTRODUCTION
The surface area of exposed metal in a trabecular-titanium acetabular component is wider compared to traditional-titanium implants. The purpose of this study is to establish if this increase in surface area can lead to a significant increase in systemic metal levels.
METHODS
19 patients with conventional acetabular component and 19 with trabecular-titanium cup were compared. Aluminum, Vanadium and Titanium in blood and urine were assessed before surgery and at intervals for 2 years. The samples were analysed using an inductively coupled plasma mass spectrometry.
RESULTS
Patients with trabecular-titanium did not have significantly higher metal ion levels compared to patients with conventional cups up to 2 years. A trend over time was statistically significant in both blood and urine for aluminum and titanium concentrations.
CONCLUSIONS
The three-dimensionality and the wide surface of the trabecular-titanium acetabular component did not affect metal ion release compared to traditional implants after 2 years.
引言
与传统钛植入物相比，小梁钛髋臼部件中暴露金属的表面积更大。本研究的目的是确定表面积的增加是否会导致全身金属水平显著升高。
方法
对19例使用传统髋臼部件的患者和19例使用小梁钛杯的患者进行比较。在手术前及术后2年期间定期评估血液和尿液中的铝、钒和钛含量。样本采用电感耦合等离子体质谱法进行分析。
结果
在长达2年的时间里，与使用传统髋臼杯的患者相比，使用小梁钛的患者金属离子水平并无显著升高。铝和钛浓度在血液和尿液中随时间变化的趋势具有统计学意义。
结论
与传统植入物相比，小梁钛髋臼部件的三维结构和宽大表面在2年后并未影响金属离子释放。
Zotero 插件