Institute of Orthopaedics and Musculoskeletal Science, University College London, Brockley Hill, Stanmore, HA7 4LP, UK.
Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, UK.
J Orthop Surg Res. 2020 Apr 19;15(1):157. doi: 10.1186/s13018-020-01665-y.
Three-dimensional (3D) printing of porous titanium implants is increasing in orthopaedics, promising enhanced bony fixation whilst maintaining design similarities with conventionally manufactured components. Our study is one of the first to non-destructively characterize 3D-printed implants, using conventionally manufactured components as a reference.
We analysed 16 acetabular cups retrieved from patients, divided into two groups: '3D-printed' (n = 6) and 'conventional' (n = 10). Coordinate-measuring machine (CMM), electron microscopy (SEM) and microcomputed tomography (micro-CT) were used to investigate the roundness of the internal cup surface, the morphology of the backside surface and the morphometric features of the porous structures of the cups, respectively. The amount of bony attachment was also evaluated.
CMM analysis showed a median roundness of 19.45 and 14.52 μm for 3D-printed and conventional cups, respectively (p = 0.1114). SEM images revealed partially molten particles on the struts of 3D-printed implants; these are a by-product of the manufacturing technique, unlike the beads shown by conventional cups. As expected, porosity, pore size, strut thickness and thickness of the porous structure were significantly higher for 3D-printed components (p = 0.0002), with median values of 72.3%, 915 μm, 498 μm and 1.287 mm (p = 0.0002). The median values of bony attachment were 84.9% and 69.3% for 3D-printed and conventional cups, respectively (p = 0.2635).
3D-printed implants are designed to be significantly more porous than some conventional components, as shown in this study, whilst still exhibiting the same shape and size. We found differences in the surface morphologies of the groups, related to the different manufacturing methods; a key finding was the presence of partially molten particles on the 3D-printed cups.
3D 打印多孔钛植入物在骨科领域的应用越来越多,有望在保持与传统制造部件设计相似的同时,增强骨固定。我们的研究是首次对 3D 打印植入物进行非破坏性特征分析的研究之一,使用传统制造的部件作为参考。
我们分析了从患者中取出的 16 个髋臼杯,将其分为两组:“3D 打印”(n=6)和“传统”(n=10)。使用坐标测量机(CMM)、电子显微镜(SEM)和微计算机断层扫描(micro-CT)分别研究内部杯表面的圆度、背面表面的形态和杯子多孔结构的形态特征,以及骨附着的量。
CMM 分析显示,3D 打印和传统杯子的平均圆度分别为 19.45μm 和 14.52μm(p=0.1114)。SEM 图像显示 3D 打印植入物的支柱上存在部分熔化的颗粒;这些是制造技术的副产品,与传统杯子上的珠子不同。不出所料,3D 打印组件的孔隙率、孔径、支柱厚度和多孔结构厚度明显更高(p=0.0002),中位数分别为 72.3%、915μm、498μm 和 1.287mm(p=0.0002)。3D 打印和传统杯子的骨附着中位数分别为 84.9%和 69.3%(p=0.2635)。
正如本研究所示,3D 打印植入物的设计目的是比某些传统部件具有更大的多孔性,同时仍保持相同的形状和尺寸。我们发现两组之间的表面形貌存在差异,这与不同的制造方法有关;一个关键发现是 3D 打印杯子上存在部分熔化的颗粒。