Bancerz-Kisiel Agata, Pieczywek Marta, Łada Piotr, Szweda Wojciech
Department of Epizootiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 2 Str., 10-719 Olsztyn, Poland.
Genes (Basel). 2018 May 3;9(5):235. doi: 10.3390/genes9050235.
is the causative agent of yersiniosis, a zoonotic disease of growing epidemiological importance with significant consequences for public health. This pathogenic species has been intensively studied for many years. Six biotypes (1A, 1B, 2, 3, 4, 5) and more than 70 serotypes of have been identified to date. The biotypes of are divided according to their pathogenic properties: the non-pathogenic biotype 1A, weakly pathogenic biotypes 2⁻5, and the highly pathogenic biotype 1B. Due to the complex pathogenesis of yersiniosis, further research is needed to expand our knowledge of the molecular mechanisms involved in the infection process and the clinical course of the disease. Many factors, both plasmid and chromosomal, significantly influence these processes. The aim of this study was to present the most important virulence markers of and their role during infection.
是耶尔森氏菌病的病原体,耶尔森氏菌病是一种人畜共患病,其流行病学重要性日益增加,对公众健康有重大影响。这种致病菌种已经被深入研究多年。迄今为止,已鉴定出六种生物型(1A、1B、2、3、4、5)和70多种血清型。的生物型根据其致病特性划分:非致病生物型1A、弱致病生物型2⁻5和高致病生物型1B。由于耶尔森氏菌病发病机制复杂,需要进一步研究以扩展我们对感染过程和疾病临床病程中涉及的分子机制的认识。许多因素,包括质粒和染色体因素,都对这些过程有显著影响。本研究的目的是介绍的最重要毒力标记及其在感染过程中的作用。