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海马脑深部电刺激:双侧颅外电极断裂后持续控制癫痫发作。

Hippocampal deep brain stimulation: persistent seizure control after bilateral extra-cranial electrode fracture.

机构信息

Department of Neurosurgery, San Bortolo Hospital, Viale Rodolfi, 37, 36100, Vicenza, Italy.

IRCS A. Meda, Conegliano, Italy.

出版信息

Neurol Sci. 2018 Aug;39(8):1431-1435. doi: 10.1007/s10072-018-3444-9. Epub 2018 May 13.

Abstract

Hippocampal deep brain stimulation (DBS) can provide an effective alternative for intractable temporal lobe epilepsy. In this case report, we describe a peculiar outcome after a post-traumatic wire-disconnection of a bilateral hippocampal DBS device. The patient presented a postoperative long-term significant reduction in seizure frequency even with an absent electric stimulation. This case gives the possibility to consider alternatives in epilepsy surgery, based on stimulation interference (lesional or electrical disturbing) in the epileptogenic zone.

摘要

海马深部脑刺激(DBS)可为耐药性颞叶癫痫提供有效替代治疗。在本病例报告中,我们描述了双侧海马 DBS 装置在创伤后出现导线断开时的一种特殊结果。尽管没有电刺激,患者术后的癫痫发作频率仍长期显著降低。该病例为基于致痫区刺激干扰(损伤性或电干扰性)的癫痫手术提供了更多选择的可能性。

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