Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Am J Epidemiol. 2018 Aug 1;187(8):1704-1713. doi: 10.1093/aje/kwy068.
Being born preterm and being raised in poverty are each linked with adverse cognitive outcomes. Using data from 5,250 singletons born in the United States in 2001 and enrolled in the Early Childhood Longitudinal Study, Birth Cohort, we examined whether household socioeconomic status (SES) modified the association between preterm birth (PTB) and children's scores on cognitive assessments at age 2 years and reading and mathematics assessments at kindergarten age. Gestational age was measured from birth certificates and categorized as early preterm, moderate preterm, late preterm, early term, and term. SES was measured at age 9 months using a composite of parental education, occupation, and income. PTB was associated with 0.1- to 0.6-standard deviation-deficits in 2-year cognitive ability and kindergarten mathematics scores and with 0.1- to 0.4-standard-deviation deficits in kindergarten reading scores. Children living in the lowest (versus highest) SES quintile scored 0.6 standard deviations lower on 2-year cognitive ability, 1.1 standard deviations lower on kindergarten reading, and 0.9 standard deviations lower on kindergarten mathematics. The association between PTB and cognitive outcomes did not differ by postnatal SES. However, children who were both born preterm and lived in lower-SES households had the poorest performance on all 3 outcomes and therefore may represent a uniquely high-risk group.
早产和贫困都会导致认知结果不良。我们利用了 2001 年在美国出生的 5250 名单胎婴儿的数据,这些婴儿参加了儿童纵向研究(早期)出生队列,研究了家庭社会经济地位(SES)是否会改变早产(PTB)与儿童 2 岁时认知评估得分以及幼儿园年龄阅读和数学评估得分之间的关联。胎龄通过出生证明测量,并分为早期早产、中度早产、晚期早产、早期足月和足月。SES 在 9 个月大时使用父母教育、职业和收入的综合指标进行测量。PTB 与 2 岁认知能力和幼儿园数学成绩的 0.1 到 0.6 标准差缺陷以及幼儿园阅读成绩的 0.1 到 0.4 标准差缺陷有关。生活在 SES 最低五分位(与最高五分位相比)的儿童在 2 岁认知能力方面得分低 0.6 个标准差,在幼儿园阅读方面得分低 1.1 个标准差,在幼儿园数学方面得分低 0.9 个标准差。PTB 与认知结果之间的关联与产后 SES 无关。然而,既早产又生活在 SES 较低家庭中的儿童在所有 3 项结果上的表现都最差,因此可能代表一个特别高风险的群体。