Lock Antonia, Rutherford Kim, Harris Midori A, Wood Valerie
Department of Genetics, Evolution and Environment, University College London, London, UK.
Department of Biochemistry, Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK.
Methods Mol Biol. 2018;1757:49-68. doi: 10.1007/978-1-4939-7737-6_4.
The fission yeast Schizosaccharomyces pombe has become well established as a model species for studying conserved cell-level biological processes, especially the mechanics and regulation of cell division. PomBase integrates the S. pombe genome sequence with traditional genetic, molecular, and cell biological experimental data as well as the growing body of large datasets generated by emerging high-throughput methods. This chapter provides insight into the curation philosophy and data organization at PomBase, and provides a guide to using PomBase for infrequent visitors and anyone considering exploring S. pombe in their research.
裂殖酵母粟酒裂殖酵母已成为研究保守的细胞水平生物学过程，特别是细胞分裂的机制和调控的经典模式物种。PomBase将粟酒裂殖酵母的基因组序列与传统的遗传、分子和细胞生物学实验数据，以及新兴高通量方法产生的大量不断增加的数据集整合在一起。本章深入介绍了PomBase的管理理念和数据组织方式，并为不常访问的用户以及任何考虑在研究中探索粟酒裂殖酵母的人提供了使用PomBase的指南。
