FlexiDot：高度可定制、具有歧义感知能力的点图，用于可视化序列分析。
FlexiDot: highly customizable, ambiguity-aware dotplots for visual sequence analyses.
机构信息
Technische Universität Dresden, School of Science, Faculty of Biology, Institute of Botany, Dresden, Germany.
出版信息
Bioinformatics. 2018 Oct 15;34(20):3575-3577. doi: 10.1093/bioinformatics/bty395.
SUMMARY
FlexiDot is a cross-platform dotplot suite generating high quality self, pairwise and all-against-all visualizations. To improve dotplot suitability for comparison of consensus and error-prone sequences, FlexiDot harbors routines for strict and relaxed handling of ambiguities and substitutions. Our shading modules facilitate dotplot interpretation and motif identification by adding information on sequence annotations and sequence similarities. Combined with collage-like outputs, FlexiDot supports simultaneous visual screening of large sequence sets, enabling dotplot use for routine analyses.
AVAILABILITY AND IMPLEMENTATION
FlexiDot is implemented in Python 2.7. Software and documentation are freely available at http://github.com/molbio-dresden/flexidot.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
FlexiDot 是一个跨平台的点阵图套件，可生成高质量的自我、成对和所有对比的可视化效果。为了提高点阵图在共识和易错序列比较方面的适用性，FlexiDot 具有严格和宽松处理歧义与替换的例程。我们的阴影模块通过添加有关序列注释和序列相似性的信息，有助于点阵图的解释和基序识别。结合类似拼贴画的输出，FlexiDot 支持大型序列集的同时视觉筛选，使点阵图可用于常规分析。
可用性和实现
FlexiDot 是用 Python 2.7 实现的。软件和文档可在 http://github.com/molbio-dresden/flexidot 上免费获得。
补充信息
补充数据可在Bioinformatics 在线获得。
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