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地中海人群健康老龄化的生活方式决定因素:多国 MEDIS 研究。

Lifestyle determinants of healthy ageing in a Mediterranean population: The multinational MEDIS study.

机构信息

Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.

Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece; Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain.

出版信息

Exp Gerontol. 2018 Sep;110:35-41. doi: 10.1016/j.exger.2018.05.008. Epub 2018 May 12.

Abstract

BACKGROUND

To evaluate modifiable, lifestyle risk factors of cardiovascular disease (CVD) among older adults, across ageing, in the Mediterranean area.

METHODS

During 2005-2017, 3131 individuals from 26 Mediterranean islands of 5 countries, ≥65 years of age, were voluntarily enrolled. Anthropometrical, clinical and socio-demographic characteristics, dietary habits, lifestyle parameters were measured through standard procedures. Analyses were performed by year and across consecutive age groups of the participants.

RESULTS

A decrease in the prevalence of current smoking (p < 0.001), engagement in physical activities (p = 0.001) and participation in social events (p = 0.001) for every year increase in age was found. Moderate alcohol drinking increased through ageing (p = 0.008), whereas adherence to Mediterranean diet remained stable, but adequate (p = 0.90). Trend analysis also revealed that a quadratic (U-shape) function better characterized the association between ageing and total cardiometabolic risk factors burden (p for trend <0.001).

CONCLUSIONS

The gaps in the understanding of factors affecting longevity and healthy ageing remain; public health authorities and stakeholders should focus on the lifestyle determinants of healthy ageing, that seems to be an effective mean for improving older peoples' health.

摘要

背景

为了评估地中海地区老年人心血管疾病(CVD)的可改变的生活方式风险因素,跨越衰老。

方法

在 2005 年至 2017 年期间,来自 5 个国家的 26 个地中海岛屿的 3131 名年龄≥65 岁的个体自愿参加了研究。通过标准程序测量了人体测量、临床和社会人口统计学特征、饮食习惯、生活方式参数。按年份和参与者的连续年龄组进行分析。

结果

发现随着年龄的增加,当前吸烟(p<0.001)、身体活动(p=0.001)和社会活动参与(p=0.001)的患病率下降。适度饮酒随着年龄的增长而增加(p=0.008),而地中海饮食的依从性保持稳定,但足够(p=0.90)。趋势分析还表明,老化与总心血管代谢危险因素负担之间的关联更适合采用二次(U 形)函数来描述(p<0.001)。

结论

对影响长寿和健康衰老的因素的理解仍存在差距;公共卫生当局和利益相关者应关注健康衰老的生活方式决定因素,这似乎是改善老年人健康的有效手段。

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