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中国北京带状疱疹疾病负担及特征的回顾性调查。

A retrospective survey on herpes zoster disease burden and characteristics in Beijing, China.

机构信息

a Beijing Municipal Center for Disease Prevention and Control , Beijing Research Center for Preventive Medicine , Beijing China.

出版信息

Hum Vaccin Immunother. 2018;14(11):2632-2635. doi: 10.1080/21645515.2018.1489193. Epub 2018 Jul 30.

Abstract

Little data are available on the overall incidence and characteristics of herpes zoster (HZ) in China, thus a community-based retrospective survey was conducted during December 2012 to March 2013 to collect HZ incident data over the past year in selected districts of Beijing, China. A total of 237 incident HZ cases were identified from 118,220 residents and majority of HZ patients (219/237, 92.4%) sought healthcare. Annual HZ incident rates were 1.90/1000 after adjusted and higher among females (2.4/1000) than males (1.7/1000). HZ rates increased with age and with a sharply rise among those aged ≥50 years particular for female. 217 cases were available for interview with 193 (88.9%) primary, 24 (11.1%) recurrent and 10 (4.6%) postherpetic neuralgia (PHN) cases respectively. No difference was shown between the primary and recurrent HZ cases in sex (P = 0.42), age (P = 0.72), times of healthcare seeking (P = 0.45), number of dermatome (P = 0.72), pain degree (P = 0.54), and hospitalization (P = 1.0). According to the survey, it can be speculated that disease burden of HZ is serious and caused at least 2.77 million cases annually in China. The recurrent HZ cases has similar characteristics to primary HZ cases. High proportion of healthcare seeking reminds that HIS records would be a feasible source for HZ surveillance to evaluate the trends and changes in China.

摘要

中国关于带状疱疹(HZ)总体发病率和特征的数据较少,因此,2012 年 12 月至 2013 年 3 月期间进行了一项基于社区的回顾性调查,以收集中国选定地区过去一年的 HZ 发病数据。从 118220 名居民中确定了 237 例带状疱疹发病病例,大多数 HZ 患者(219/237,92.4%)寻求医疗服务。调整后,HZ 的年发病率为 1.90/1000,女性(2.4/1000)高于男性(1.7/1000)。HZ 发病率随年龄增长而增加,特别是≥50 岁的人群发病率急剧上升,女性更为明显。217 例可进行访谈,其中原发性 217 例(193 例,88.9%),复发性 217 例(24 例,11.1%),带状疱疹后神经痛(PHN)217 例(10 例,4.6%)。原发性和复发性 HZ 病例在性别(P=0.42)、年龄(P=0.72)、就诊次数(P=0.45)、皮肤节段数(P=0.72)、疼痛程度(P=0.54)和住院治疗(P=1.0)方面无差异。根据调查结果,可以推测 HZ 的疾病负担严重,在中国每年至少造成 277 万例病例。复发性 HZ 病例与原发性 HZ 病例具有相似的特征。高比例的寻求医疗服务提醒我们,HIS 记录将是 HZ 监测的一种可行来源,可用于评估中国的趋势和变化。

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