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141例病毒感染后嗅觉障碍患者的临床特征分析

[Analysis of clinical characteristics of 141 patients with postviral olfactory dysfunction].

作者信息

Tian J, Wei Y X, Li L, Sun Z F, Wang B Q

机构信息

Shanxi Medical University, Taiyuan, 030001, China.

Department of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 May 20;31(10):749-752. doi: 10.13201/j.issn.1001-1781.2017.10.003.

Abstract

The aim of this study is to investigate the clinical features of the patients with postviral olfactory dysfunction (PVOD). Clinical information of 141 consecutive outpatients with PVOD were collected and analyzed based on a questionnaire, including age, gender, months of onset, and symptoms. Sniffin'Sticks Test was used as a psychophysical olfactory test to evaluate olfactory function. Retrospective analysis of 141 patients with PVOD, the male to female ratio of patients was 1.0:2.3. The severity of olfactory dysfunction was found no significant difference between the man and the women (χ2=0.05,>0.05). Patients aged from 30 to 40 years old and 50 to 60 years of age were vulnerable to PVOD. The most common nasal symptoms at the times of upper respiratory infection (URI) were nasal obstruction, rhinorrhea and sneezing, together with other symptoms, such as sore throat, sputum and cough. Analysis of clinical characteristics in a large sample shows that gender, age may be related to PVOD. However, our understanding of this complex disease is still limited and much more studies are necessary.

摘要

本研究旨在调查病毒性嗅觉功能障碍(PVOD)患者的临床特征。基于一份问卷收集并分析了141例连续门诊PVOD患者的临床信息,包括年龄、性别、发病月份和症状。使用嗅觉棒测试作为心理物理学嗅觉测试来评估嗅觉功能。对141例PVOD患者进行回顾性分析,患者男女比例为1.0:2.3。发现男性和女性之间嗅觉功能障碍的严重程度无显著差异(χ2=0.05,>0.05)。30至40岁和50至60岁的患者易患PVOD。上呼吸道感染(URI)时最常见的鼻部症状是鼻塞、流涕和打喷嚏,以及其他症状,如咽痛、咳痰和咳嗽。对大量样本的临床特征分析表明,性别、年龄可能与PVOD有关。然而,我们对这种复杂疾病的了解仍然有限,还需要更多的研究。

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