a Vittala International Institute Of Ophthalmology & Prabha Eye Clinic and Research Center , Bangalore, India.
b Vision Research Foundation, Sankara Nethralaya , Chennai, India.
Ocul Immunol Inflamm. 2019;27(5):805-807. doi: 10.1080/09273948.2018.1468472. Epub 2018 May 17.
: To report an interesting case of bilateral conjunctival granulomas in a young lady with hypereosiniophilic syndrome. : Retrospective interventional case report : A 37-year-old lady presented with irritation and redness in both eyes of 15-day duration. She had a history of abdominal pain and diarrhea since 8 months for which she has been extensively investigated including a positron emission tomography (PET) scan and an ileal biopsy which showed chronic granulomatous inflammation with eosinophils. Ocular examination revealed multiple bilateral conjunctival granulomas. Conjunctival biopsies revealed granulomatous inflammation with plenty of eosinophils and flame figure configuration. Peripheral blood smear showed increased absolute eosinophil count and eosinophilia. Stool analysis was normal. She did not have abdominal symptoms or recurrence of granulomas. : The rare association of bilateral conjunctival granulomas with hypereosinophilic syndrome has been described in this report.
回顾性介入病例报告。
一位 37 岁女性因双眼刺激和发红就诊,病程 15 天。她有 8 个月的腹痛和腹泻病史,已进行广泛检查,包括正电子发射断层扫描(PET)扫描和回肠活检,显示伴有嗜酸性粒细胞的慢性肉芽肿性炎症。眼部检查显示多个双侧结膜肉芽肿。结膜活检显示伴有大量嗜酸性粒细胞的肉芽肿性炎症和火焰状外观。外周血涂片显示绝对嗜酸性粒细胞计数增加和嗜酸性粒细胞增多。粪便分析正常。她没有腹部症状或肉芽肿复发。
本报告描述了嗜酸性粒细胞增多综合征伴双侧结膜肉芽肿的罕见关联。