Barkana Y, Zadok D, Herbert M, Kornberg A, Nemet P
Department of Ophthalmology, Assaf Harofe Medical Center, Beer Yaacov, Zerifin, Israel.
Am J Ophthalmol. 2001 Jun;131(6):796-7. doi: 10.1016/s0002-9394(00)00895-3.
To report atypical kerato-conjunctivitis as a manifestation of Hodgkin disease.
Case report.
A 19-year old woman presented with conjunctival nodules and corneal infiltrates. Diffuse lymph node enlargement occurred, but not in the preauricular or submandibular areas. Extensive microbiologic examination was negative. Conjunctival biopsy showed noncaseating granulomas. Inguinal lymph node biopsy showed Hodgkin lymphoma, and chemotherapy was instituted. Ocular signs resolved after 6 weeks, but a corneal scar remained.
The appearance of conjunctival granulomas and corneal infiltrates may represent a clinical manifestation of Hodgkin lymphoma.
报告非典型角膜结膜炎作为霍奇金病的一种表现。
病例报告。
一名19岁女性出现结膜结节和角膜浸润。出现弥漫性淋巴结肿大,但耳前或下颌下区域未出现。广泛的微生物学检查为阴性。结膜活检显示非干酪样肉芽肿。腹股沟淋巴结活检显示霍奇金淋巴瘤,并开始化疗。眼部体征在6周后消退,但角膜瘢痕仍然存在。
结膜肉芽肿和角膜浸润的出现可能代表霍奇金淋巴瘤的一种临床表现。