人体静脉对心房利钠因子的反应性。
Venous responsiveness to atrial natriuretic factor in man.
作者信息
Ford G A, Eichler H G, Hoffman B B, Blaschke T F
机构信息
Department of Medicine, Stanford University School of Medicine, California 94305.
出版信息
Br J Clin Pharmacol. 1988 Dec;26(6):797-9. doi: 10.1111/j.1365-2125.1988.tb05322.x.
Abstract
The venorelaxant effect of atrial natriuretic factor in man was studied using the dorsal hand vein technique. Infusion of met-ANF to preconstricted veins at doses up to 240 ng min-1 in 11 healthy male subjects caused only minimal venorelaxation. Atrial natriuretic factor is unlikely to have a significant venorelaxant effect at physiological doses in man.
摘要
采用手背静脉技术研究了心房利钠因子对人体的静脉舒张作用。在11名健康男性受试者中，以高达240 ng·min-1的剂量将甲硫氨酸心房利钠因子注入预先收缩的静脉，仅引起最小程度的静脉舒张。在生理剂量下，心房利钠因子对人体不太可能有显著的静脉舒张作用。
相似文献
1
Venous responsiveness to atrial natriuretic factor in man.人体静脉对心房利钠因子的反应性。
Br J Clin Pharmacol. 1988 Dec;26(6):797-9. doi: 10.1111/j.1365-2125.1988.tb05322.x.
2
The influence of the atrial natriuretic factor on venous tone in man.心房利钠因子对人体静脉张力的影响。
Int J Clin Pharmacol Res. 1989;9(4):255-60.
3
Hemodynamic effects of atrial natriuretic factor in young and elderly subjects.心房利钠因子对青年人和老年人的血流动力学影响。
Clin Pharmacol Ther. 1990 Aug;48(2):179-88. doi: 10.1038/clpt.1990.133.
4
Atrial natriuretic factor as a vasodilator agent in hypertensive patients.心房利钠因子作为高血压患者的血管扩张剂
Am J Med Sci. 1990 Aug;300(2):78-82. doi: 10.1097/00000441-199008000-00002.
5
Vascular responses to local atrial natriuretic peptide infusion in man.人体对局部输注心房利钠肽的血管反应。
Br J Clin Pharmacol. 1988 Sep;26(3):245-51. doi: 10.1111/j.1365-2125.1988.tb05273.x.
6
Effect of atrial natriuretic peptide on hemodynamics of the stage 21 chick embryo.
Pediatr Res. 1990 Jun;27(6):557-60. doi: 10.1203/00006450-199006000-00003.
7
Disposition and dynamics of atrial natriuretic factor in conscious rabbits.清醒家兔心房利钠因子的分布与动态变化
J Pharmacol Exp Ther. 1989 Oct;251(1):328-33.
8
Negative feedback of atrial natriuretic peptides.
J Clin Endocrinol Metab. 1994 May;78(5):1128-34. doi: 10.1210/jcem.78.5.8175968.
9
10
Central C-type natriuretic peptide but not atrial natriuretic factor lowers blood pressure and adrenocortical secretion in normal conscious sheep.中枢C型利钠肽而非心房利钠因子可降低正常清醒绵羊的血压和肾上腺皮质分泌。
Endocrinology. 1992 Oct;131(4):1721-6. doi: 10.1210/endo.131.4.1396317.
引用本文的文献
1
Atrial natriuretic peptide alters neither capillary filtration nor vascular compliance of both skin and skeletal muscle of humans.心钠素对人体皮肤和骨骼肌的毛细血管滤过及血管顺应性均无影响。
Basic Res Cardiol. 1994 Mar-Apr;89(2):192-205. doi: 10.1007/BF00788737.
2
Clinical pharmacology, physiology and pathophysiology of superficial veins--2.浅静脉的临床药理学、生理学及病理生理学——2.
Br J Clin Pharmacol. 1994 Oct;38(4):289-305. doi: 10.1111/j.1365-2125.1994.tb04357.x.
本文引用的文献
1
A new technique for recording compliance of human hand veins.一种记录人体手部静脉顺应性的新技术。
Br J Clin Pharmacol. 1981 Mar;11(3):237-43. doi: 10.1111/j.1365-2125.1981.tb00527.x.
2
Regional vasorelaxant selectivity of atrial natriuretic factor in isolated rabbit vessels.心房利钠因子在离体兔血管中的局部血管舒张选择性。
Life Sci. 1985 Sep 16;37(11):1073-9. doi: 10.1016/0024-3205(85)90599-5.
3
Absence of age-related changes in venous responsiveness to nitroglycerin in vivo in humans.
Clin Pharmacol Ther. 1987 Nov;42(5):521-4. doi: 10.1038/clpt.1987.191.
4
Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man.
J Pharmacol Exp Ther. 1986 Dec;239(3):802-7.
5
Direct effect of alpha-human atrial natriuretic peptide on human vasculature in vivo and in vitro.
Clin Sci (Lond). 1988 Feb;74(2):207-11. doi: 10.1042/cs0740207.
6
Nitroprusside, but not ANF inhibits venoconstriction in an in situ rat model.在原位大鼠模型中，硝普钠而非心房钠尿肽可抑制静脉收缩。
Eur J Pharmacol. 1987 Nov 17;143(3):299-304. doi: 10.1016/0014-2999(87)90453-5.
7
Atriopeptin: a cardiac hormone intimately involved in fluid, electrolyte, and blood-pressure homeostasis.心房肽：一种与体液、电解质及血压稳态密切相关的心脏激素。
N Engl J Med. 1986 Mar 27;314(13):828-34. doi: 10.1056/NEJM198603273141306.
8
The relaxant effects of atrial natriuretic factor on vascular smooth muscle.心房利钠因子对血管平滑肌的舒张作用。
Life Sci. 1985 Sep 23;37(12):1081-7. doi: 10.1016/0024-3205(85)90351-0.
9
Renal, haemodynamic, and hormonal effects of human alpha atrial natriuretic peptide in healthy volunteers.人α-心房利钠肽对健康志愿者的肾脏、血流动力学及激素的影响
Lancet. 1985 Mar 9;1(8428):545-9. doi: 10.1016/s0140-6736(85)91207-3.
Zotero 插件