人体静脉对心房利钠因子的反应性。
Venous responsiveness to atrial natriuretic factor in man.
作者信息
Ford G A, Eichler H G, Hoffman B B, Blaschke T F
机构信息
Department of Medicine, Stanford University School of Medicine, California 94305.
出版信息
Br J Clin Pharmacol. 1988 Dec;26(6):797-9. doi: 10.1111/j.1365-2125.1988.tb05322.x.
Abstract
The venorelaxant effect of atrial natriuretic factor in man was studied using the dorsal hand vein technique. Infusion of met-ANF to preconstricted veins at doses up to 240 ng min-1 in 11 healthy male subjects caused only minimal venorelaxation. Atrial natriuretic factor is unlikely to have a significant venorelaxant effect at physiological doses in man.
摘要
采用手背静脉技术研究了心房利钠因子对人体的静脉舒张作用。在11名健康男性受试者中，以高达240 ng·min-1的剂量将甲硫氨酸心房利钠因子注入预先收缩的静脉，仅引起最小程度的静脉舒张。在生理剂量下，心房利钠因子对人体不太可能有显著的静脉舒张作用。
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本文引用的文献
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Atriopeptin: a cardiac hormone intimately involved in fluid, electrolyte, and blood-pressure homeostasis.心房肽：一种与体液、电解质及血压稳态密切相关的心脏激素。
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