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精神药理学与心血管疾病

Psychopharmacology and Cardiovascular Disease.

机构信息

Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York.

Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York.

出版信息

J Am Coll Cardiol. 2018 May 22;71(20):2346-2359. doi: 10.1016/j.jacc.2018.03.458.

Abstract

This review discusses common mental health disorders and their associations with cardiovascular disease risks. Commonly found mental health disorders include depression, anxiety, and personality types. The link between depression and cardiovascular disease mortality has been established. Depression is also common in patients with heart failure. In addition to discussing psychological disorders, a review of psychotropic drugs is also included. Drugs are described for therapy for depression and anxiety, as well as associations with cardiovascular drug-drug interactions. Drug-drug interactions are more common and potentially dangerous in elderly patients, in whom the conditions often coexist. The most common drug-drug interactions involve the P450 system of enzymes.

摘要

这篇综述讨论了常见的心理健康障碍及其与心血管疾病风险的关联。常见的心理健康障碍包括抑郁症、焦虑症和人格类型。已经确定了抑郁症与心血管疾病死亡率之间的联系。抑郁症在心力衰竭患者中也很常见。除了讨论心理障碍外,还包括对精神药物的综述。药物用于治疗抑郁症和焦虑症,以及与心血管药物相互作用的关联。药物相互作用在老年患者中更为常见且潜在危险,因为这些情况往往同时存在。最常见的药物相互作用涉及 P450 酶系统。

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