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自闭症与巴勒斯坦人群的营养状况有关吗?巴勒斯坦微量营养素调查的结果。

Could Autism Be Associated With Nutritional Status in the Palestinian population? The Outcomes of the Palestinian Micronutrient Survey.

作者信息

Altamimi Mohammad

机构信息

Department of Nutrition and Food technology, An-Najah National University, Nablus, Palestine.

出版信息

Nutr Metab Insights. 2018 May 10;11:1178638818773078. doi: 10.1177/1178638818773078. eCollection 2018.

Abstract

BACKGROUND

Autism spectrum disorder is a neurodevelopmental disorder. It is believed that the cause of autism is multifactorial, where genetic predispositions interact with environmental factors. In this context, micronutrients play a crucial role.

OBJECTIVE

To present evidence on current micronutrient status in Palestine and highlight its possible role in increasing problems of neurodevelopment disorders in general and autism in particular.

METHOD

Analytical review of results.

RESULTS AND CONCLUSIONS

The Palestinian Micronutrient Survey was conducted to assess micronutrient status in most vulnerable groups and also micronutrient deficiencies. The data from Palestinian population showed severe anaemia due to iron, Zn, B12, and folic acid deficiencies. One in every 3 Palestinian pregnant women is anaemic. Moreover, 78.2% and 87.1% of lactating mothers from the West Bank and Gaza Strip are Zn deficient. For children from 6 to 59 months old, 1 in every 4 boys and 1 in every 5 girls are considered anaemic. Similar trend was found with respect to vitamins E, D, A, and folic acid. We reviewed the literature that linked micronutrient deficiencies to neurodevelopmental disorders and expected the number of neurodevelopmental disorder cases, including autism, to increase.

摘要

背景

自闭症谱系障碍是一种神经发育障碍。人们认为自闭症的病因是多因素的,其中遗传易感性与环境因素相互作用。在这种情况下,微量营养素起着至关重要的作用。

目的

提供关于巴勒斯坦当前微量营养素状况的证据,并强调其在增加一般神经发育障碍尤其是自闭症问题方面可能发挥的作用。

方法

对结果进行分析性综述。

结果与结论

开展了巴勒斯坦微量营养素调查,以评估最脆弱群体的微量营养素状况以及微量营养素缺乏情况。来自巴勒斯坦人群的数据显示,由于铁、锌、维生素B12和叶酸缺乏导致严重贫血。每3名巴勒斯坦孕妇中就有1人贫血。此外,约旦河西岸和加沙地带78.2%和87.1%的哺乳期母亲缺锌。对于6至59个月大的儿童,每4名男孩和每5名女孩中就有1人被认为贫血。在维生素E、D、A和叶酸方面也发现了类似趋势。我们查阅了将微量营养素缺乏与神经发育障碍联系起来的文献,并预计包括自闭症在内的神经发育障碍病例数量将会增加。

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