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中东地区 2015-2016 年发生的由 A/ASIA/G-VII 病毒谱系引起的口蹄疫。

Foot-and-Mouth Disease in the Middle East Caused by an A/ASIA/G-VII Virus Lineage, 2015-2016.

出版信息

Emerg Infect Dis. 2018 Jun;24(6):1073-1078. doi: 10.3201/eid2406.170715.

DOI:10.3201/eid2406.170715
PMID:29774839
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6004861/
Abstract

Phylogenetic analyses of foot-and-mouth disease type A viruses in the Middle East during 2015-2016 identified viruses belonging to the A/ASIA/G-VII lineage, which originated in the Indian subcontinent. Changes in a critical antigenic site within capsid viral protein 1 suggest possible evolutionary pressure caused by an intensive vaccination program.

摘要

2015-2016 年期间中东地区的口蹄疫 A 型病毒的系统进化分析鉴定出属于 A/ASIA/G-VII 谱系的病毒,该谱系起源于印度次大陆。衣壳病毒蛋白 1 内一个关键抗原位点的变化表明,密集的疫苗接种计划可能导致了进化压力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/937f/6004861/c70343b6ed5e/17-0715-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/937f/6004861/9cd46f20b7fa/17-0715-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/937f/6004861/c70343b6ed5e/17-0715-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/937f/6004861/9cd46f20b7fa/17-0715-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/937f/6004861/c70343b6ed5e/17-0715-F2.jpg

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