Fürst B, Luckner M
Martin-Luther-Universität, Sektion Pharmazie, Halle, Saale.
Pharmazie. 1988 Nov;43(11):744-8.
Human beings and higher animals contain compounds which interact with the Na+/K+-ATPase of the heart muscle and other organs like the cardiac glycosides, and bind to cardiac glycoside-specific antibodies [endogenous digitalis-like substance(s), EDLS]. EDLS cause increased natriuresis. The level of EDLS of the blood is raised under physiological stress situations (e.g., pregnancy and delivery and at certain pathophysiological conditions (e.g., hypertony). The EDLS are low molecular compounds. As yet their chemical structure is unknown.
人类和高等动物体内含有与心肌及其他器官的钠钾ATP酶相互作用的化合物，如强心苷，并能与强心苷特异性抗体结合[内源性类洋地黄物质（EDLS）]。EDLS可导致尿钠排泄增加。在生理应激状态下（如妊娠和分娩）以及某些病理生理状况下（如高血压），血液中EDLS的水平会升高。EDLS是低分子化合物。其化学结构至今仍不清楚。
