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儿童机器人辅助腹腔镜肾盂成形术中外置肾盂输尿管支架与内置输尿管支架的结果比较。

Outcomes of externalized pyeloureteral versus internal ureteral stent in pediatric robotic-assisted laparoscopic pyeloplasty.

机构信息

Division of Urology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Department of Urology, Einstein Healthcare Network, Philadelphia, PA, USA.

出版信息

J Pediatr Urol. 2018 Oct;14(5):450.e1-450.e6. doi: 10.1016/j.jpurol.2018.04.012. Epub 2018 May 7.

Abstract

INTRODUCTION

After pyeloplasty, urinary drainage options include internal double-J (DJ) ureteral stents or externalized pyeloureteral (EPU) stents, which can avoid bladder symptoms and additional anesthetic exposure from stent removal. Comparative outcome studies, however, are lacking following primary pediatric robotic-assisted laparoscopic pyeloplasty (RALP).

OBJECTIVE

To compare operative success, operative time, hospitalization, and postoperative complications of EPU versus DJ stents following RALP.

STUDY DESIGN

Consecutive children undergoing primary RALP from 10/2013 to 9/2015 were retrospectively identified. Data collected included patient demographics, stent type and duration, postoperative complications, and operative success. To control for confounding by indication for EPU stent, propensity score weighting was used to balance baseline covariates. Weighted regression analyses compared between-group differences in study outcomes.

RESULTS

At median follow-up of 12.3 months, 44 and 17 patients underwent DJ and EPU stenting, respectively. At baseline, DJ stent patients were older than EPU stent patients (median 7.7 vs 1.2 years, P = 0.01) and were less likely to be on postoperative antibiotic prophylaxis (25 vs 76%, P < 0.001). After weighting, these differences disappeared. All EPU stents were removed in the outpatient clinic; all DJ stents were removed under anesthesia. On weighted regression analyses (Summary Fig.), EPU stents had no different associations than DJ stents with operative success (95 vs 94%, between-group difference 1%, 95% CI -11, 13; P = 0.86), complications, or operative time, but did have 0.6 of a day more hospitalization (95% CI 0.04, 1.2; P = 0.04).

DISCUSSION

Patients receiving EPU stents were different at baseline from those receiving DJ stents. After propensity score weighting balanced these covariates, EPU stents were associated with similar operative success, complications, and operative time to DJ stents. Further study is warranted in larger prospective cohorts.

CONCLUSION

Use of EPU stents provided a viable alternative, particularly in younger patients, to DJ stenting with comparable success and complications, while avoiding the need for an additional anesthetic.

摘要

简介

肾盂成形术后,可选择留置内部双 J(DJ)输尿管支架或外部化肾盂输尿管(EPU)支架,这可以避免膀胱症状和支架取出带来的额外麻醉暴露。然而,对于原发性小儿机器人辅助腹腔镜肾盂成形术(RALP)后,缺乏比较性的结果研究。

目的

比较 EPU 支架与 DJ 支架在 RALP 后的手术成功率、手术时间、住院时间和术后并发症。

研究设计

回顾性地确定了 2013 年 10 月至 2015 年 9 月期间接受原发性 RALP 的连续患儿。收集的数据包括患者人口统计学、支架类型和留置时间、术后并发症和手术成功率。为了控制 EPU 支架指征的混杂因素,使用倾向评分加权来平衡基线协变量。加权回归分析比较了组间研究结果的差异。

结果

中位随访 12.3 个月时,44 例患者接受 DJ 支架留置,17 例患者接受 EPU 支架留置。在基线时,DJ 支架患者比 EPU 支架患者年龄更大(中位数 7.7 岁比 1.2 岁,P=0.01),术后接受抗生素预防治疗的可能性更小(25%比 76%,P<0.001)。经过加权后,这些差异消失了。所有 EPU 支架均在门诊诊所中取出,所有 DJ 支架均在全身麻醉下取出。在加权回归分析(总结图)中,EPU 支架与 DJ 支架在手术成功率(95%比 94%,组间差异 1%,95%CI-11,13;P=0.86)、并发症或手术时间方面无差异,但住院时间延长了 0.6 天(95%CI 0.04,1.2;P=0.04)。

讨论

接受 EPU 支架的患者与接受 DJ 支架的患者在基线时存在差异。经过倾向评分加权平衡这些协变量后,EPU 支架与 DJ 支架相比,手术成功率、并发症和手术时间相似。需要在更大的前瞻性队列中进一步研究。

结论

使用 EPU 支架是一种可行的替代方法,特别是在年轻患者中,与 DJ 支架留置相比,成功率和并发症相似,同时避免了额外麻醉的需要。

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