生物发光成像中的生物正交化学。
Bioorthogonal chemistry in bioluminescence imaging.
机构信息
Institute of Chemical Biology, Department of Chemistry, Imperial College London, London SW7 2AZ, UK.
Laboratory of Bioorganic Chemistry and Molecular Imaging, Institute of Chemical Sciences and Engineering (ISIC), Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland.
出版信息
Drug Discov Today. 2018 Sep;23(9):1584-1590. doi: 10.1016/j.drudis.2018.05.022. Epub 2018 May 18.
Bioorthogonal chemistry has developed significant over the past few decades, to the particular benefit of molecular imaging. Bioluminescence imaging (BLI) along with other imaging modalities have significantly benefitted from this chemistry. Here, we review bioorthogonal reactions that have been used to signific antly broaden the application range of BLI.
生物正交化学在过去几十年中得到了显著发展，特别有益于分子成像。生物发光成像（BLI）和其他成像方式都从这种化学中受益良多。在这里，我们回顾了已经被用于显著拓宽 BLI 应用范围的生物正交反应。
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