处方药物监测计划的强制性审查及其对阿片类药物和苯二氮䓬类药物配药的影响。
Mandatory review of a prescription drug monitoring program and impact on opioid and benzodiazepine dispensing.
机构信息
Department of Behavioral Medicine and Psychiatry, School of Medicine, West Virginia University, 930 Chestnut Ridge Road, Morgantown, WV, 26505-2854, USA.
School of Pharmacy, West Virginia University, P.O. Box 9500, Morgantown, WV, 26506-9500, USA.
出版信息
Drug Alcohol Depend. 2018 Jul 1;188:169-174. doi: 10.1016/j.drugalcdep.2018.03.036. Epub 2018 May 1.
Abstract
BACKGROUND
The purpose of this study is to determine whether Ohio House Bill 341, which mandated the use of Ohio's Prescription Drug Monitoring Program (PDMP), was an effective regulatory strategy to reduce opioid and benzodiazepine dispensing.
METHOD
Secondary analysis of Ohio's PDMP data on prescription opioids and benzodiazepines dispensed from November 2014 to March 2017. An interrupted time series analysis was conducted to determine if there was a significant change in the quantity of opioids and benzodiazepines dispensed.
RESULTS
After HB341 became effective in April 2015, there was a statistically significant decrease in the monthly quantity (number of pills) opioids and benzodiazepines dispensed in Ohio. There was a modest increase in the mean days' supply of opioids and no change in the mean morphine equivalent dose.
CONCLUSIONS
Legislation in Ohio requiring prescribers to check the PDMP was effective in reducing the quantity of opioids and benzodiazepines dispensed.
摘要
背景
本研究旨在确定俄亥俄州众议院法案 341 是否是一项有效的监管策略，以减少阿片类药物和苯二氮䓬类药物的配给，该法案要求使用俄亥俄州的处方药监测计划（PDMP）。
方法
对俄亥俄州 PDMP 数据进行二次分析，这些数据涉及 2014 年 11 月至 2017 年 3 月开具的处方类阿片类药物和苯二氮䓬类药物。采用中断时间序列分析来确定开具的阿片类药物和苯二氮䓬类药物的数量是否有显著变化。
结果
HB341 于 2015 年 4 月生效后，俄亥俄州开具的阿片类药物和苯二氮䓬类药物的每月数量（药丸数量）有统计学意义的下降。阿片类药物的平均供应天数略有增加，而吗啡等效剂量无变化。
结论
俄亥俄州立法要求医生检查 PDMP，这一举措有效地减少了阿片类药物和苯二氮䓬类药物的配给量。
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