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[铜含量对CoCrMoCu合金抗菌性能及耐腐蚀性的影响]

[Effects of copper content on the antibacterial performance and corrosion resistance of CoCrMoCu alloy].

作者信息

Yin Zhun, Ren Yi-Bin, Zhan De-Song

机构信息

Dept. of Prosthetics, School of Stomatology, China Medical University, Shenyang 110002, China;Central Laboratory, School of Stomatology, China Medical University, Shenyang 110002, China;Liaoning Province Key Laboratory of Oral Disease, Shenyang 110002, China;Liaoning Province Oral Disease Translational Medicine Research Center, Shenyang 110002, China.

Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Apr 1;36(2):178-183. doi: 10.7518/hxkq.2018.02.012.

Abstract

OBJECTIVE

This study aimed to determine the effects of copper content on the corrosion resistance of CoCrMoCu alloy and its in vitro antibacterial performance.

METHODS

CoCrMoCu specimens with different Cu contents (2%, 3%, 5%, and 7%) were prepared by vacuum melting method. CoCrMo without Cu served as control. The corrosion resistance of the specimens was measured by electrochemistry. The antibacterial effects of the specimens on Staphylococcus aureus and Escherichia coli were analyzed by coating-film method.

RESULTS

Compared with CoCrMo without Cu, the addition of 2%-5% Cu to CoCrMo improved the pitting and uniform corrosion of CoCrMo alloy and decreased the corrosion current density. The antibacterial performance of CoCrMoCu alloy increased with increased Cu content. The antibacterial rate of alloy was 99% when Cu content exceeded 5%.

CONCLUSIONS

Cu addition had a statistically significant influence on the corrosion resistance and antibacterial performance of CoCrMoCu. CoCrMoCu has better corrosion resistance and antibacterial performance when Cu content is 5%.

摘要

目的

本研究旨在确定铜含量对CoCrMoCu合金耐腐蚀性及其体外抗菌性能的影响。

方法

采用真空熔炼法制备不同铜含量(2%、3%、5%和7%)的CoCrMoCu试样。不含铜的CoCrMo作为对照。通过电化学方法测量试样的耐腐蚀性。采用涂膜法分析试样对金黄色葡萄球菌和大肠杆菌的抗菌效果。

结果

与不含铜的CoCrMo相比,在CoCrMo中添加2%-5%的铜可改善CoCrMo合金的点蚀和均匀腐蚀,并降低腐蚀电流密度。CoCrMoCu合金的抗菌性能随铜含量的增加而增强。当铜含量超过5%时,合金的抗菌率为99%。

结论

添加铜对CoCrMoCu的耐腐蚀性和抗菌性能有统计学上的显著影响。当铜含量为5%时,CoCrMoCu具有较好的耐腐蚀性和抗菌性能。

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本文引用的文献

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A dual function of copper in designing regenerative implants.铜在设计再生植入物中的双重功能。
Biomaterials. 2015 Mar;44:36-44. doi: 10.1016/j.biomaterials.2014.12.022. Epub 2015 Jan 10.
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A new antibacterial titanium-copper sintered alloy: preparation and antibacterial property.一种新型抗菌钛铜烧结合金:制备与抗菌性能。
Mater Sci Eng C Mater Biol Appl. 2013 Oct;33(7):4280-7. doi: 10.1016/j.msec.2013.06.016. Epub 2013 Jun 26.

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