National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, 200025, China.
Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, People's Republic of China.
Infect Dis Poverty. 2018 May 21;7(1):50. doi: 10.1186/s40249-018-0432-5.
Human African trypanosomiasis (HAT) is one of the most complex parasitic diseases known to humankind. It usually occurs in endemic areas in Africa, but is occasionally detected in returning travelers and migrants in non-endemic countries.
In August 2017, a case of HAT was diagnosed in China in a traveler returning from the Masai Mara area in Kenya and the Serengeti area in Tanzania. The traveler visited Africa from 23 July to 5 August, 2017. Upon return to China, she developed a fever (on 8 August), and Trypanosoma brucei rhodesiense infection was confirmed by laboratory tests (on 14 August) including observation of parasites in blood films and by polymerase chain reaction. She was treated with pentamidine followed by suramin, and recovered 1 month later.
This is the first imported rhodesiense HAT case reported in China. This case alerts clinical and public health workers to be aware of HAT in travelers, and expatriates and migrants who have visited at-risk areas in Africa.
人类非洲锥虫病（HAT）是人类已知的最复杂的寄生虫病之一。它通常发生在非洲的流行地区，但偶尔也会在非流行国家的返回旅行者和移民中发现。
2017 年 8 月，中国确诊了一例从肯尼亚马赛马拉地区和坦桑尼亚塞伦盖蒂地区返回的旅行者感染 HAT。该旅行者于 2017 年 7 月 23 日至 8 月 5 日期间前往非洲。返回中国后，她于 8 月 8 日开始发烧，并于 8 月 14 日通过实验室检查（包括血片观察寄生虫和聚合酶链反应）证实感染了罗得西亚锥虫。她接受了喷他脒治疗，随后又接受了苏拉明治疗，一个月后康复。
这是中国首例报告的输入性罗得西亚锥虫病病例。该病例提醒临床和公共卫生工作者注意旅行者以及前往非洲高危地区的侨民和移民中的 HAT。
