Sudarshi Darshan, Brown Mike
University College London, London, UK
Hospital for Tropical Diseases, London, UK, and senior lecturer in tropical medicine, London School of Hygiene and Tropical Medicine, London, UK.
Clin Med (Lond). 2015 Feb;15(1):70-3. doi: 10.7861/clinmedicine.15-1-70.
Human African trypanosomiasis (HAT) or sleeping sickness is a parasitic disease, acquired by the bite of an infected tsetse fly. In non-endemic countries HAT is rare, and therefore the diagnosis may be delayed leading to potentially fatal consequences. In this article the clinical presentation, diagnosis and treatment of the two forms of HAT are outlined. Rhodesiense HAT is an acute illness that presents in tourists who have recently visited game parks in Eastern or Southern Africa, whereas Gambiense HAT has a more chronic clinical course, in individuals from West or Central Africa.
人类非洲锥虫病(HAT)即昏睡病,是一种寄生虫病,通过感染的采采蝇叮咬传播。在非流行国家,HAT较为罕见,因此诊断可能会延迟,从而导致潜在的致命后果。本文概述了两种形式的HAT的临床表现、诊断和治疗。罗德西亚型HAT是一种急性疾病,出现在近期去过东非或南非野生动物园的游客中,而冈比亚型HAT在来自西非或中非的个体中临床病程更为慢性。