• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于无均整器射线束的数字兆伏成像探测器的剂量率响应

Dose rate response of Digital Megavolt Imager detector for flattening filter-free beams.

作者信息

Xu Zhigang, Kim Jinkoo, Han James, Hsia An Ting, Ryu Samuel

机构信息

Department of Radiation Oncology, Stony Brook University Hospital, Stony Brook, NY, USA.

出版信息

J Appl Clin Med Phys. 2018 Jul;19(4):141-147. doi: 10.1002/acm2.12358. Epub 2018 May 21.

DOI:10.1002/acm2.12358
PMID:29781165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6036399/
Abstract

In this study we investigated the dose rate response characteristics of the Digital Megavolt Imager (DMI) detector, including panel saturation, linearity, and imager ghosting effects for flattening filter-free (FFF) beams. The DMI detector dose rate response characteristics were measured as a function of dose rate on a Varian TrueBeam machine. Images were acquired at dose rates ranging from 400 to 1400 MU/min for 6XFFF and 400 to 2400 MU/min for 10XFFF. Line profiles and central portal doses derived from the images were analyzed and compared. The linearity was verified by acquiring images with incremental Monitor Unit (MU) ranging from 5 to 500 MU. Ghosting effects were studied at different dose rates. Finally, for validation, test plans with optimal fluence were created and measured with different dose rates. All test plans were analyzed with a Gamma criteria of 3%-3 mm and 10% dose threshold. Our study showed that there was no panel saturation observed from the profile comparison even at the maximum dose rate of 2400 MU/min. The central portal doses showed a slight decrease (1.013-1.008 cGy/MU for 6XFFF, and 1.020-1.009 cGy/MU for 10XFFF) when dose rate increased (400-1400 MU/min for 6XFFF, and 400-2400 MU/min for 10XFFF). The linearity of the DMI detector response was better than 0.5% in the range of 20-500 MU for all energies. The residual image was extremely small and statistically undetectable. The Gamma index measured with the test plans decreased from 100% to 97.8% for 6XFFF when dose rate increased from 400 to 1400 MU/min. For 10XFFF, the Gamma index decreased from 99.9% to 91.5% when dose rate increased from 400 to 2400 MU/min. We concluded that the Portal Dosimetry system for the TrueBeam using DMI detector can be reliably used for IMRT and VMAT QA for FFF energies.

摘要

在本研究中,我们调查了数字兆伏成像仪(DMI)探测器的剂量率响应特性,包括平板饱和、线性度以及无均整器(FFF)射束的成像仪重影效应。在瓦里安TrueBeam机器上,测量了DMI探测器剂量率响应特性随剂量率的变化情况。对于6XFFF射束,在400至1400 MU/分钟的剂量率范围内采集图像;对于10XFFF射束,在400至2400 MU/分钟的剂量率范围内采集图像。对从图像中得出的线轮廓和中心射野剂量进行了分析和比较。通过采集增量监测单位(MU)范围为5至500 MU的图像来验证线性度。在不同剂量率下研究了重影效应。最后,为进行验证,创建了具有最佳注量的测试计划,并在不同剂量率下进行测量。所有测试计划均采用3%-3毫米的伽马标准和10%的剂量阈值进行分析。我们的研究表明,即使在2400 MU/分钟的最大剂量率下,从轮廓比较中也未观察到平板饱和现象。当剂量率增加时(6XFFF为400至1400 MU/分钟,10XFFF为400至2400 MU/分钟),中心射野剂量略有下降(6XFFF为1.013 - 1.008 cGy/MU,10XFFF为1.020 - 1.009 cGy/MU)。对于所有能量,DMI探测器响应的线性度在20至500 MU范围内优于0.5%。残留图像极小,在统计学上无法检测到。当剂量率从400增加到1400 MU/分钟时,6XFFF测试计划的伽马指数从100%降至97.8%。对于10XFFF,当剂量率从400增加到2400 MU/分钟时,伽马指数从99.

相似文献

1
Dose rate response of Digital Megavolt Imager detector for flattening filter-free beams.用于无均整器射线束的数字兆伏成像探测器的剂量率响应
J Appl Clin Med Phys. 2018 Jul;19(4):141-147. doi: 10.1002/acm2.12358. Epub 2018 May 21.
2
EPID-based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams.基于电子射野影像装置(EPID)的剂量测定法,用于验证aS1200电子射野影像装置(EPID)和FFF束流的调强放疗(IMRT)平面剂量分布。
J Appl Clin Med Phys. 2016 Nov 8;17(6):292-304. doi: 10.1120/jacmp.v17i6.6336.
3
Dosimetric Validation of Digital Megavolt Imager for Flattening Filter Free Beams in the Pre-Treatment Quality Assurance of Stereotactic Body Radiation Therapy for Liver Metastases.用于肝脏转移立体定向体部放射治疗的术前质量保证中,在自由匀场射束下对数字兆伏级图像进行剂量学验证。
Asian Pac J Cancer Prev. 2020 Jun 1;21(6):1659-1665. doi: 10.31557/APJCP.2020.21.6.1659.
4
Evaluation of an aSi-EPID with flattening filter free beams: applicability to the GLAaS algorithm for portal dosimetry and first experience for pretreatment QA of RapidArc.评估带有平扫滤波器的非晶硅电子射野影像装置:在 GLAaS 算法用于门控剂量学中的适用性,以及 RapidArc 治疗前 QA 的初步经验
Med Phys. 2013 Nov;40(11):111719. doi: 10.1118/1.4824923.
5
Practical approach for pretreatment verification of IMRT with flattening filter free(FFF) beams using Varian Portal Dosimetry.使用瓦里安射野剂量仪对无均整器(FFF)射束的调强放射治疗(IMRT)进行治疗前验证的实用方法。
J Appl Clin Med Phys. 2014 Jan 8;16(1):4934. doi: 10.1120/jacmp.v16i1.4934.
6
[Measurement of peak correction factor of Farmer chamber for calibration of flattening filter free (FFF) clinical photon beams].[用于无均整器(FFF)临床光子束校准的 Farmer 电离室峰值校正因子的测量]
Magy Onkol. 2015 Jun;59(2):119-23. Epub 2015 Mar 26.
7
Feasibility of portal dosimetry for flattening filter-free radiotherapy.用于无均整器放射治疗的射野剂量测定的可行性
J Appl Clin Med Phys. 2016 Jan 8;17(1):112-120. doi: 10.1120/jacmp.v17i1.5686.
8
Characteristics of flattening filter free beams at low monitor unit settings.低剂量照射时使用不带过滤板的射束的特点。
Med Phys. 2013 Nov;40(11):112101. doi: 10.1118/1.4824920.
9
Commissioning of portal dosimetry using a novel method for flattening filter-free photon beam in a nontrue beam linear accelerator.在非真正束流直线加速器中,使用一种新型方法对无均整器光子束进行射野剂量测定的调试。
J Cancer Res Ther. 2019 Jan-Mar;15(1):223-230. doi: 10.4103/jcrt.JCRT_1181_16.
10
Improvements in dose accuracy delivered with static-MLC IMRT on an integrated linear accelerator control system.静态多叶准直器调强放射治疗在集成直线加速器控制系统上剂量精度的改进。
Med Phys. 2012 May;39(5):2456-62. doi: 10.1118/1.3701778.

引用本文的文献

1
Commissioning and clinical evaluation of a novel high-resolution quality assurance digital detector array for SRS and SBRT.用于 SRS 和 SBRT 的新型高分辨率质量保证数字探测器阵列的委托和临床评估。
J Appl Clin Med Phys. 2024 Apr;25(4):e14258. doi: 10.1002/acm2.14258. Epub 2024 Jan 4.
2
Determination of the electronic portal imaging device pixel-sensitivity-map for quality assurance applications. Part 2: Photon beam dependence.用于质量保证应用的电子射野影像装置像素灵敏度图的确定。第 2 部分:光子束依赖性。
J Appl Clin Med Phys. 2022 Jun;23(6):e13602. doi: 10.1002/acm2.13602. Epub 2022 Apr 15.
3
Planar EPID-Based Dosimetry for SRS and SRT Patient-Specific QA.

本文引用的文献

1
EPID-based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams.基于电子射野影像装置(EPID)的剂量测定法,用于验证aS1200电子射野影像装置(EPID)和FFF束流的调强放疗(IMRT)平面剂量分布。
J Appl Clin Med Phys. 2016 Nov 8;17(6):292-304. doi: 10.1120/jacmp.v17i6.6336.
2
On flattening filter-free portal dosimetry.关于无均整器的射野剂量测定法
J Appl Clin Med Phys. 2016 Jul 8;17(4):132-145. doi: 10.1120/jacmp.v17i4.6147.
3
Feasibility of portal dosimetry for flattening filter-free radiotherapy.用于无均整器放射治疗的射野剂量测定的可行性
基于平面电子射野影像装置的立体定向放射外科和立体定向放疗患者特异性质量保证剂量测定法
Life (Basel). 2021 Oct 30;11(11):1159. doi: 10.3390/life11111159.
4
Verification of an optimizer algorithm by the beam delivery evaluation of intensity-modulated arc therapy plans.通过强度调制弧形治疗计划的束流传输评估来验证优化器算法。
Radiol Oncol. 2021 Nov 19;55(4):508-515. doi: 10.2478/raon-2021-0046.
5
Assessing the feasibility of single target radiosurgery quality assurance with portal dosimetry.评估单靶点放射外科质量保证的可行性:应用门控剂量测定法。
J Appl Clin Med Phys. 2019 May;20(5):135-140. doi: 10.1002/acm2.12578. Epub 2019 Apr 1.
J Appl Clin Med Phys. 2016 Jan 8;17(1):112-120. doi: 10.1120/jacmp.v17i1.5686.
4
Impact of dose rate on accuracy of intensity modulated radiation therapy plan delivery using the pretreatment portal dosimetry quality assurance and setting up the workflow at hospital levels.剂量率对使用治疗前门控剂量测定质量保证的调强放射治疗计划执行准确性的影响以及在医院层面建立工作流程
J Med Phys. 2015 Oct-Dec;40(4):226-32. doi: 10.4103/0971-6203.170786.
5
Evaluation of an aSi-EPID with flattening filter free beams: applicability to the GLAaS algorithm for portal dosimetry and first experience for pretreatment QA of RapidArc.评估带有平扫滤波器的非晶硅电子射野影像装置:在 GLAaS 算法用于门控剂量学中的适用性,以及 RapidArc 治疗前 QA 的初步经验
Med Phys. 2013 Nov;40(11):111719. doi: 10.1118/1.4824923.
6
Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy.放射治疗中用于自由平扫(FFF)光子束质量保证的参数定义。
Med Phys. 2012 Oct;39(10):6455-64. doi: 10.1118/1.4754799.
7
Experimental investigation of the response of an a-Si EPID to an unflattened photon beam from an Elekta Precise linear accelerator.非晶硅电子射野影像装置对医科达Precise直线加速器的非均整光子束响应的实验研究。
Med Phys. 2009 Apr;36(4):1318-29. doi: 10.1118/1.3089424.
8
A literature review of electronic portal imaging for radiotherapy dosimetry.用于放射治疗剂量测定的电子射野影像系统的文献综述。
Radiother Oncol. 2008 Sep;88(3):289-309. doi: 10.1016/j.radonc.2008.07.008. Epub 2008 Aug 14.
9
Dosimetric properties of photon beams from a flattening filter free clinical accelerator.来自无均整器临床加速器的光子束剂量学特性
Phys Med Biol. 2006 Apr 7;51(7):1907-17. doi: 10.1088/0031-9155/51/7/019. Epub 2006 Mar 21.
10
The use of an aSi-based EPID for routine absolute dosimetric pre-treatment verification of dynamic IMRT fields.基于非晶硅的电子射野影像装置用于动态调强放疗射野的常规绝对剂量预处理验证。
Radiother Oncol. 2004 May;71(2):223-34. doi: 10.1016/j.radonc.2004.02.018.