Xu Yan'an, Jiang Dianming
Department of Orthopedics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, P.R.China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2016 Jun 8;30(6):781-784. doi: 10.7507/1002-1892.20160159.
To summarize the physicochemical properties, manufacturing technique, and biological characteristics of porous tantalum and its application progress and related problems in spinal surgery.
The domestic and foreign related literature about porous tantalum was summarized and analyzed.
Porous tantalum is characterized by high porosity, high coefficient of friction, low elastic modulus, good biocompatibility, and superior osseointegration capability. Its manufacture methods include chemical vapor deposition and infiltration technique, foam impregnation and powder metallurgy technique, and heat treatment method. Good clinical efficacy has achieved in the application of porous tantalum interbody fusion Cage in cervical and lumbar fusion surgery, but there is controversy in spinal fusion rate, especially in cervical fusion rate. Surface modification can increase the osseointegration capability of porous tantalum and intervertebral bony fusion.
Good clinical efficacy has achieved in the application of porous tantalum interbody fusion Cage in lumbar fusion surgery, while there is a dispute in cervical fusion surgery. In order to further observation, studies with more patients and longer follow-up would be needed.
总结多孔钽的理化性质、制造技术、生物学特性及其在脊柱外科的应用进展和相关问题。
对国内外有关多孔钽的相关文献进行总结分析。
多孔钽具有孔隙率高、摩擦系数高、弹性模量低、生物相容性好和骨整合能力强等特点。其制造方法包括化学气相沉积与渗透技术、泡沫浸渍与粉末冶金技术以及热处理方法。多孔钽椎间融合器在颈椎和腰椎融合手术中的应用取得了良好的临床疗效，但在脊柱融合率方面存在争议，尤其是颈椎融合率。表面改性可提高多孔钽的骨整合能力和椎间骨融合。
多孔钽椎间融合器在腰椎融合手术中的应用取得了良好的临床疗效，而在颈椎融合手术中存在争议。为进一步观察，需要更多患者和更长随访时间的研究。
