使用度普利尤单抗治疗的嗜酸性环状红斑。
Eosinophilic annular erythema treated with dupilumab.
作者信息
Gordon Samantha C, Robinson Sarah N, Abudu Minawaer, Her Michelle, Deverapalli Sandyha, Levin Adrianne, Schmidt Birgitta A R, Gellis Stephen E, Rosmarin David
机构信息
Department of Dermatology, Tufts Medical Center, Boston, MA, USA.
Department of Dermatology, School of Medicine, Harvard University, Boston, MA, USA.
出版信息
Pediatr Dermatol. 2018 Jul;35(4):e255-e256. doi: 10.1111/pde.13533. Epub 2018 May 23.
Eosinophilic annular erythema is a rare, benign, recurrent condition characterized by annular skin lesions, tissue eosinophilia, and resistance to a variety of treatments. There are fewer than 30 cases reported in the English literature, 7 of which are in children. We present a case of recurrent eosinophilic annular erythema in an adolescent that was successfully treated with dupilumab, an interleukin-4 receptor alpha antagonist.
嗜酸性环状红斑是一种罕见的、良性的、复发性疾病，其特征为环状皮肤损害、组织嗜酸性粒细胞增多以及对多种治疗方法耐药。英文文献报道的病例少于30例，其中7例为儿童患者。我们报告了1例青少年复发性嗜酸性环状红斑患者，该患者使用白细胞介素-4受体α拮抗剂度普利尤单抗治疗成功。
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