Gordon Samantha C, Robinson Sarah N, Abudu Minawaer, Her Michelle, Deverapalli Sandyha, Levin Adrianne, Schmidt Birgitta A R, Gellis Stephen E, Rosmarin David
Department of Dermatology, Tufts Medical Center, Boston, MA, USA.
Department of Dermatology, School of Medicine, Harvard University, Boston, MA, USA.
Pediatr Dermatol. 2018 Jul;35(4):e255-e256. doi: 10.1111/pde.13533. Epub 2018 May 23.
Eosinophilic annular erythema is a rare, benign, recurrent condition characterized by annular skin lesions, tissue eosinophilia, and resistance to a variety of treatments. There are fewer than 30 cases reported in the English literature, 7 of which are in children. We present a case of recurrent eosinophilic annular erythema in an adolescent that was successfully treated with dupilumab, an interleukin-4 receptor alpha antagonist.
嗜酸性环状红斑是一种罕见的、良性的、复发性疾病，其特征为环状皮肤损害、组织嗜酸性粒细胞增多以及对多种治疗方法耐药。英文文献报道的病例少于30例，其中7例为儿童患者。我们报告了1例青少年复发性嗜酸性环状红斑患者，该患者使用白细胞介素-4受体α拮抗剂度普利尤单抗治疗成功。
