Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
Tob Control. 2019 Mar;28(2):152-160. doi: 10.1136/tobaccocontrol-2017-054152. Epub 2018 May 23.
Tobacco flavours are an important regulatory concept in several jurisdictions, for example in the USA, Canada and Europe. The European Tobacco Products Directive 2014/40/EU prohibits cigarettes and roll-your-own tobacco having a characterising flavour. This directive defines characterising flavour as 'a clearly noticeable smell or taste other than one of tobacco […]'. To distinguish between products with and without a characterising flavour, we trained an expert panel to identify characterising flavours by smelling.
An expert panel (n=18) evaluated the smell of 20 tobacco products using self-defined odour attributes, following Quantitative Descriptive Analysis. The panel was trained during 14 attribute training, consensus training and performance monitoring sessions. Products were assessed during six test sessions. Principal component analysis, hierarchical clustering (four and six clusters) and Hotelling's T-tests (95% and 99% CIs) were used to determine differences and similarities between tobacco products based on odour attributes.
The final attribute list contained 13 odour descriptors. Panel performance was sufficient after 14 training sessions. Products marketed as unflavoured that formed a cluster were considered reference products. A four-cluster method distinguished cherry-flavoured, vanilla-flavoured and menthol-flavoured products from reference products. Six clusters subdivided reference products into tobacco leaves, roll-your-own and commercial products.
An expert panel was successfully trained to assess characterising odours in cigarettes and roll-your-own tobacco. This method could be applied to other product types such as e-cigarettes. Regulatory decisions on the choice of reference products and significance level are needed which directly influences the products being assessed as having a characterising odour.
烟草口味是多个司法管辖区的一个重要监管概念,例如在美国、加拿大和欧洲。2014/40/EU 号欧洲烟草制品指令禁止具有特征风味的香烟和自卷烟草。该指令将特征风味定义为“不同于烟草的明显气味或味道[...]”。为了区分具有和不具有特征风味的产品,我们培训了一个专家小组,通过嗅觉来识别特征风味。
一个专家小组(n=18)使用自我定义的气味属性,按照定量描述性分析,评估了 20 种烟草产品的气味。该小组在 14 次属性培训、共识培训和性能监测会议期间接受了培训。产品在六次测试会议期间进行了评估。主成分分析、层次聚类(四聚体和六聚体)和 Hotelling 的 T 检验(95%和 99%置信区间)用于根据气味属性确定烟草产品之间的差异和相似性。
最终属性列表包含 13 个气味描述符。经过 14 次培训会议,小组的表现已经足够。被归类为无香味且形成一个聚类的产品被视为参考产品。四聚体方法将樱桃味、香草味和薄荷醇味产品与参考产品区分开来。六聚体将参考产品细分为烟叶、自卷和商业产品。
一个专家小组成功地接受了培训,以评估香烟和自卷烟草中的特征气味。该方法可应用于其他产品类型,如电子烟。需要对参考产品和显著性水平的选择做出监管决策,这直接影响被评估为具有特征气味的产品。