Scotland Kymora B, Hubosky Scott G, Tanimoto Ryuta, Cooper Robert, Healy Kelly A, Bagley Demetrius H
Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Urology, Thomas Jefferson University Hospital, Philadelphia, PA.
Urology. 2018 Aug;118:30-35. doi: 10.1016/j.urology.2018.03.052. Epub 2018 May 21.
To define the need for emergent intervention between patients with simultaneous bilateral ureteral calculi (SBUC) compared to unilateral ureteral calculi (UUC). Patients with SBUC represent a potential urological emergency due to possible anuria or electrolyte imbalance. While conventional practice mandates immediate intervention in these patients, little data exist to define the rate of these events.
Records of all patients with ureteral stones treated ureteroscopically over an 11-year period were reviewed to identify those with SBUC. Patient presenting characteristics, time from diagnosis to intervention, and postoperative outcomes were noted. To determine the need for emergent intervention, we compared metabolic and infectious parameters between SBUC patients and age- and sex-matched patients with UUC.
A total of 3800 patients presented with ureteral calculi including 42 (1.1%) with SBUC. Two-thirds of patients with SBUC had an established diagnosis of nephrolithiasis. Among the 42 patients with SBUC, 11 (26.2%) were considered emergent due to metabolic (5 of 11, 45.5%), infectious (1 of 11, 9.1%), or both metabolic and infectious indications (5 of 11, 45.5%). No patients required acute dialysis before surgical intervention. Compared to patients with UUC, those with SBUC were significantly more likely to require emergent management (P = .03, odds ratio 2.3). Univariate and multivariate analyses showed this to be due to anuria (P = .001) and acidosis (P = .003).
SBUC is an uncommon condition and, in this series, only the minority of patients presented emergently. Therefore, patients with SBUC can often be managed electively if counseled on clinical signs warranting emergent medical attention. Appropriately selected patients have excellent outcomes following single stage bilateral ureteroscopy.
明确双侧输尿管结石(SBUC)患者与单侧输尿管结石(UUC)患者相比进行紧急干预的必要性。SBUC患者因可能出现无尿或电解质失衡而存在潜在的泌尿外科急症情况。虽然传统做法要求对这些患者立即进行干预,但几乎没有数据来确定这些情况的发生率。
回顾了11年间所有接受输尿管镜治疗的输尿管结石患者的记录,以确定患有SBUC的患者。记录患者的呈现特征、从诊断到干预的时间以及术后结果。为了确定紧急干预的必要性,我们比较了SBUC患者与年龄和性别匹配的UUC患者的代谢和感染参数。
共有3800例患者出现输尿管结石,其中42例(1.1%)为SBUC。三分之二的SBUC患者已确诊为肾结石。在42例SBUC患者中,11例(26.2%)因代谢(11例中的5例,45.5%)、感染(11例中的1例,9.1%)或代谢和感染指征并存(11例中的5例,45.5%)而被视为紧急情况。在手术干预前没有患者需要急性透析。与UUC患者相比,SBUC患者更有可能需要紧急处理(P = 0.03,优势比2.3)。单因素和多因素分析表明,这是由于无尿(P = 0.001)和酸中毒(P = 0.003)。
SBUC是一种罕见的情况,在本系列中,只有少数患者出现紧急情况。因此,如果对患者进行关于需要紧急医疗关注的临床体征的咨询,SBUC患者通常可以进行择期治疗。经适当选择的患者在一期双侧输尿管镜检查后有良好的结果。