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长期工作时间与老年人群中高敏 C 反应蛋白的关系:韩国国家健康和营养检查调查(KNHANES)2015 年。

The Association Between Long Working Hours and High-Sensitivity C-Reactive Protein in Older Aged Individuals: The Korea National Health and Nutrition Examination Survey (KNHANES) 2015.

机构信息

Department of Public Health and Hygiene, Andong Public Health Center, Andong, Korea (Dr Lee); Department of Medicine, Graduate School, The Catholic University of Korea, Seoul, Korea (Dr Lee); and Department of Occupational and Environmental Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea (Dr Kim).

出版信息

J Occup Environ Med. 2018 Sep;60(9):775-780. doi: 10.1097/JOM.0000000000001359.

DOI:10.1097/JOM.0000000000001359
PMID:29794555
Abstract

OBJECTIVE

The objective of this study was to show the association of high-sensitivity C-reactive protein (hs-CRP) level with working hours in different age groups.

METHODS

We used data from Korean National Health and Nutrition Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) of variables for elevated hs-CRP (>3.0 mg/L) were generated with logistic regression models. Significant variables were verified with an adjusted multivariate logistic model after stratification of age groups.

RESULTS

Working for more than 55 hours per week was associated with elevated hs-CRP level in the old-ages group (≥ 60 years old: OR 2.18, 95% CI 1.07 to 4.45). Working for 40 to 55 hours per week was associated with decreased hs-CRP in the young-ages group (OR 0.58, 95% CI 0.37 to 0.93).

CONCLUSION

Working hours appear to influence the levels of hs-CRP in individuals aged older than 60 years.

摘要

目的

本研究旨在探讨不同年龄段人群中高敏 C 反应蛋白(hs-CRP)水平与工作时间的相关性。

方法

我们使用了来自韩国国家健康与营养调查的数据。采用 logistic 回归模型生成 hs-CRP(>3.0mg/L)升高的变量的比值比(ORs)和 95%置信区间(CIs)。在按年龄组分层后,通过调整后的多变量 logistic 模型对有意义的变量进行验证。

结果

每周工作超过 55 小时与老年组(≥60 岁)hs-CRP 水平升高相关(OR 2.18,95%CI 1.07 至 4.45)。每周工作 40 至 55 小时与年轻组(OR 0.58,95%CI 0.37 至 0.93)hs-CRP 降低相关。

结论

工作时间似乎会影响 60 岁以上人群的 hs-CRP 水平。

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